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Open AccessPrevalence and serotype distribution of nasopharyngeal carriage of Streptococcus pneumoniae among healthy children under 5 years of age in Hainan Province, China
The thirteen-valent pneumococcal conjugate vaccine (PCV13) is not included in the national immunization program and is administered voluntarily with informed consent in China. In preparation for assessing the ...
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Article
Open AccessPrognostic Value of Blood Urea Nitrogen for Short-Term Mortality in Patients with Infective Endocarditis
Blood urea nitrogen (BUN) is a metabolic product validated to be an independent risk factor in the prognosis of several diseases. However, the prognostic value of BUN in patients with infective endocarditis (I...
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Article
Open AccessInfection of sheep by Echinococcus multilocularis in Gansu, China: evidence from mitochondrial and nuclear DNA analysis
In the normal life cycle of the parasite (Echinococcus multilocularis) that causes alveolar echinococcosis, domestic and wild carnivores act as definitive hosts, and rodents act as intermediate hosts. The present...
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Article
Open AccessWorldwide productivity and research trend of publications concerning tumor immune microenvironment (TIME): a bibliometric study
As the complexity and diversity of the tumor immune microenvironment (TIME) are becoming better understood, burgeoning research has progressed in this field. However, there is a scarcity of literature specific...
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Article
Open AccessIncreased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis
Coronavirus disease 2019 (COVID-19) can involve persistence, sequelae, and other clinical complications that last weeks to months to evolve into long COVID-19. Exploratory studies have suggested that interleuk...
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Article
Open AccessThe first case of Escherichia fergusonii with biofilm in China and literature review
Escherichia fergusonii is a rare opportunistic pathogen in humans and animals, especially with biofilm.
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Article
Open AccessCorrection to: Efficacy and Pharmacodynamic Target Attainment for Ceftazidime–Avibactam Off-Label Dose Regimens in Patients with Continuous or Intermittent Venovenous Hemodialysis: Two Case Reports
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Open AccessEfficacy and Pharmacodynamic Target Attainment for Ceftazidime–Avibactam Off-Label Dose Regimens in Patients with Continuous or Intermittent Venovenous Hemodialysis: Two Case Reports
Limited data are available for ceftazidime–avibactam (CZA) dosing in patients receiving renal replacement therapy, especially the data on the dosing in patients receiving intermittent hemodialysis (IHD). In th...
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Article
Open AccessGlobal proteomic profiling of multiple organs of cats (Felis catus) and proteome-transcriptome correlation during acute Toxoplasma gondii infection
Toxoplasma gondii is a protozoan parasite which can infect almost all warm-blooded animals and humans. Understanding the differential expression of proteins and transcripts associated with T. gondii infection in ...
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Article
Open AccessDoes Monitoring Total and Free Polymyxin B1 Plasma Concentrations Predict Polymyxin B-Induced Nephrotoxicity? A Retrospective Study in Critically Ill Patients
The correlation between total and free polymyxin B (PMB including PMB1 and PMB2) exposure in vivo and acute kidney injury (AKI) remains obscure. This study explores the relationships between plasma exposure of...
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Article
Open AccessTowards a global One Health index: a potential assessment tool for One Health performance
A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animal...
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Article
Open AccessSix-month follow-up of functional status in discharged patients with coronavirus disease 2019
The long-term functional outcome of discharged patients with coronavirus disease 2019 (COVID-19) remains unresolved. We aimed to describe a 6-month follow-up of functional status of COVID-19 survivors.
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Article
Open AccessA qualitative study of perspectives on access to tuberculosis health services in **gaze, China
Tuberculosis (TB) is a major global health threat and the leading infectious disease cause of death worldwide. Access to and retention in TB care remains a challenge for patients, particularly those living in ...
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Article
Open AccessIncreased circulating level of interleukin-6 and CD8+ T cell exhaustion are associated with progression of COVID-19
Coronavirus disease 2019 (COVID-19) is pandemic. It is critical to identify COVID-19 patients who are most likely to develop a severe disease. This study was designed to determine the clinical and epidemiologi...
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Article
Open AccessKinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19: a descriptive study
To explore the kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19.
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Open AccessSuccessful treatment of mycobacterial infection associated hemophagocytic lymphohistiocytosis with etoposide and anti-tuberculous therapy: a case report
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially life-threatening disorder characterized by an exacerbated but ineffective inflammatory response, which can be classified as primary and second...
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ART-Related Diseases in HIV/AIDS Patients
With the wider usage of ART in clinical practice, the side effects of ART have been of concern. ART-associated side effects and toxicity include gastrointestinal adverse effects, liver toxicity, cutaneous and ...
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Article
Open AccessA community-based comprehensive intervention to reduce syphilis infection among low-fee female sex workers in China: a matched-pair, community-based randomized study
Low-fee female sex workers (FSWs) are at high risk of acquiring and spreading human immunodeficiency virus (HIV)/sexually transmitted diseases (STDs) in China. There is an urgent need to develop comprehensive ...
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Open AccessTransmission of rabies through solid organ transplantation: a notable problem in China
Due to the increasing number of DCD transplantations since 2015, the transmission of rabies through solid organ transplantation has become a notable problem in China and has attracted the attention of the public.
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Open AccessDog vaccination with EgM proteins against Echinococcus granulosus
Dogs play a pivotal role in the transmission of cystic echinococcosis (CE), a zoonosis caused by the tapeworm Echinococcus granulosus. We showed previously that dogs vaccinated with two E. granulosus adult-worm s...