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  1. Article

    Publisher Correction: The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

    Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker… in Nature (2023)

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    The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

    Natural killer (NK) cells kill infected, transformed and stressed cells when an activating NK cell receptor is triggered1. Most NK cells and some innate lymphoid cells express the activating receptor NKp46, encod...

    Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker… in Nature (2023)

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    Article

    FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

    Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells assembles large complexes called inflammasomes, which activate inflammatory caspases to process cytokines (IL-1β) and gasdermin...

    Jun Jacob Hu, **ng Liu, Shiyu **a, Zhibin Zhang, Ying Zhang… in Nature Immunology (2020)