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  1. Article

    Open Access

    Angiogenesis-associated pathways play critical roles in neonatal sepsis outcomes

    Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and mechanistic insights have hampered our abilities to develop prophylactic or therapeutic interventions. Biomarkers in human ...

    Mario Fidanza, Julie Hibbert, Erica Acton, Danny Harbeson… in Scientific Reports (2024)

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    Article

    Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro

    Preterm infants are at high risk of infection and have distinct pathogen recognition responses. Suggested mechanisms include soluble mediators that enhance cellular levels of cAMP. The aim of this study was to...

    Tobias Strunk, Simon D. van Haren, Julie Hibbert, Matthew Pettengill… in Pediatric Research (2020)

  3. No Access

    Article

    Identification of generic and pathogen-specific cord blood monocyte transcriptomes reveals a largely conserved response in preterm and term newborn infants

    Escherichia coli and Staphylococcus epidermidis are predominant causes of neonatal sepsis, particularly affecting preterm infants. Susceptibility to infection has been attributed to “immature...

    Emma de Jong, David G. Hancock, Julie Hibbert… in Journal of Molecular Medicine (2018)

  4. Article

    Phagocytosis of neonatal pathogens by peripheral blood neutrophils and monocytes from newborn preterm and term infants

    Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), Staphylococcu...

    Amy Prosser, Julie Hibbert, Tobias Strunk, Chooi Heen Kok… in Pediatric Research (2013)

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