8 Result(s)
within
Julian Barwell
Epidemiology
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Article
The management of families affected by hereditary non-polyposis colorectal cancer (HNPCC)
This study assessed current practice and methods for improvement in the management of families with hereditary non-polyposis colorectal cancer (HNPCC). HNPCC families registered at five London Genetics Centres...
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Article
Supporting families with Cancer: A patient centred survivorship model of care
In 2011, the Leicestershire Clinical Genetics Department in collaboration with Macmillan Cancer Support initiated a project called Supporting Families with Cancer (SFWC). The project aimed to raise awareness ...
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Article
Open AccessBaseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls
In the United Kingdom, current screening guidelines for TP53 germline mutation carriers solely recommends annual breast MRI, despite the wide spectrum of malignancies typically seen in this group. This study soug...
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Article
Inclusion of diverse populations in genomic research and health services: Genomix workshop report
Clinical genetic services and genomic research are rapidly develo** but, historically, those with the greatest need are the least to benefit from these advances. This encompasses low-income communities, incl...
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Article
Open AccessProstate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition...
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Open AccessErratum: Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Correction to: British Journal of Cancer (2018) 118, 266–276; doi:10.1038/bjc.2017.429; published online 04 January 2018 The authors would like to acknowledge the following information for this manuscript: Chr...
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Article
Open AccessMendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
Height and body mass index (BMI) are associated with higher ovarian cancer risk in the general population, but whether such associations exist among BRCA1/2 mutation carriers is unknown.
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Article
Open AccessEvaluation of tumour surveillance protocols and outcomes in von Hippel-Lindau disease in a national health service
Von Hippel-Lindau (VHL) disease is an inherited tumour predisposition syndrome and a paradigm for the importance of early diagnosis and surveillance. However, there is limited information on the “real world” m...
