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    Article

    Pharmacokinetics and Pharmacodynamics of Nonsteroidal Androgen Receptor Ligands

    Testosterone and structurally related anabolic steroids have been used to treat hypogonadism, muscle wasting, osteoporosis, male contraception, cancer cachexia, anemia, and hormone replacement therapy in aging...

    Wenqing Gao, Juhyun Kim, James T. Dalton in Pharmaceutical Research (2006)

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    OpenMendel: a cooperative programming project for statistical genetics

    Statistical methods for genome-wide association studies (GWAS) continue to improve. However, the increasing volume and variety of genetic and genomic data make computational speed and ease of data manipulation...

    Hua Zhou, Janet S. Sinsheimer, Douglas M. Bates, Benjamin B. Chu in Human Genetics (2020)

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    Complete genome sequence of a putative novel cytorhabdovirus isolated from Rudbeckia sp.

    Through high-throughput RNA sequencing, we discovered a putative new cytorhabdovirus in the seeds of Rudbeckia sp., which we have tentatively named “rudbeckia virus 1” (RudV1). Its complete 12,502-nt genomic sequ...

    Da-Som Lee, Juhyun Kim, Minji Jun, Sanghyun Shin, Seong-** Lee in Archives of Virology (2022)

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    Complete genome and molecular characterization of a putative novel citrivirus from Rudbeckia sp.

    We identified a tentative novel positive-strand RNA virus from Rudbeckia sp., namely, Rudbeckia citrivirus A (RuCVA). The complete genome sequence of the novel virus was 8821 nucleotides in length, excluding the ...

    Juhyun Kim, Minji Jun, Da-Som Lee, Eun ** Jeon, Sanghyun Shin in Virus Genes (2023)

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    Open Access

    A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung

    We present an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27 individual donors. Our large-scale single-cell profilin...

    Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee in Experimental & Molecular Medicine (2023)