Skip to main content

and
  1. No Access

    Article

    Mouse chromosome 2

    Linda D. Siracusa, Catherine M. Abbott, Judith L. Morgan in Mammalian Genome (1997)

  2. No Access

    Article

    Hepatitis B virus transgenic mouse model of chronic liver disease

    A model for hepatitis B virus-associated chronic liver disease has been made using cloned hepatitis B virus DNA as a transgene in a severe combined immunodeficient host. These mice consistently support virus g...

    Jonathan Larkin, Marcy Clayton, Bill Sun, Claire E. Perchonock in Nature Medicine (1999)

  3. Article

    Open Access

    Developmental constraint through negative pleiotropy in the zygomatic arch

    Previous analysis suggested that the relative contribution of individual bones to regional skull lengths differ between inbred mouse strains. If the negative correlation of adjacent bone lengths is associated...

    Christopher J. Percival, Rebecca Green, Charles C. Roseman, Daniel M. Gatti in EvoDevo (2018)

  4. Article

    Open Access

    Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches

    Here, we describe an expansion of the typical DNA size limitations associated with CRISPR knock-in technology, more specifically, the physical extent to which mouse genomic DNA can be replaced with donor (in t...

    Tiffany Leidy-Davis, Kai Cheng, Leslie O. Goodwin, Judith L. Morgan in Scientific Reports (2018)