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Article
Open AccessMeasurement of Δ9THC and metabolites in the brain and peripheral tissues after intranasal instillation of a nanoformulation
Comparative bioavailability of cannabinoids following their administration by dosing routes has been studied previously, but there are no quantitative reports of distribution of Δ9THC, nor its metabolites, across...
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Chapter
A Case Report: Using Multimodalities to Examine a Professional Pianist with Focal Dystonia
Task-specific dystonia is characterized by excessive muscle contractions producing abnormal postures. These structural and functional changes are known to be a result of maladaptive neuroplasticity to prolonged, ...
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Protocol
Method for Stimulation of Hippocampal Neurogenesis by Transient Microneedle Insertion
Brief stereotaxic insertion and removal of a microneedle into the hippocampus of mice result in stimulation of hippocampal neurogenesis. This approach has been previously applied to a mouse model of Alzheimer’...
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Article
Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning
Drugs that modulate serotonin (5-HT) synaptic concentrations impact neurogenesis and hippocampal (HPC)-dependent learning. The primary objective is to determine the extent to which psilocybin (PSOP) modulates ...
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Article
Open AccessThe potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review
There are no effective interventions that significantly forestall or reverse neurodegeneration and cognitive decline in Alzheimer's disease. In the past decade, the generation of new neurons has been recognize...
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Chapter
The Search for Neural Progenitors in Bone Marrow and Umbilical Cord Blood
The study of hematopoiesis, the generation of blood cell lines throughout life, has provided conceptual, experimental, and therapeutic approaches useful to all stem cell biologists. From a clinical perspective...
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Chapter
Relationship of Organochlorine Pesticides to Parkinsonism
Anecdotal reports and several epidemiological studies have pointed to pesticide exposure as a risk factor for Parkinsons Disease (PD). We have reviewed the evidence in the literature and from our laboratory wh...
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Article
The role of mitochondrial DNA in Huntington's disease
Huntington's disease is generally considered to be a late-onset neurodegenerative disorder, which follows a protracted course of deteriorating motor control and cognitive impairment. However, in a minority of ...
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Article
The role of mitochondrial DNA in Huntington’s disease
Huntington’s disease is generally considered to be a late-onset neurodegenerative disorder, which follows a protracted course of deteriorating motor control and cognitive impairment. However, in a minority of ...
