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Article
Does MBCT Affect Psychodynamic Defense Mechanisms and Self-Rated Mindfulness in Older Adults?
Mindfulness-Based Cognitive Therapy (MBCT) interventions have become widely used to improve psychological outcomes for various populations and shown effective in reducing symptoms of anxiety and depression. Ps...
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From Benevolent Patriarchy to Gender Transformation: A Case Study of Pakistan’s “We Can End Violence against Women” Program
Ending violence against women and promoting gender equality have long been on the agenda of Pakistani women and human rights activists. In Pakistan and many other develo** countries, initiatives that engage ...
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Article
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
Genome-wide copy number analyses of human cancers identified a frequent 5p13 amplification in several solid tumour types, including lung (56%), ovarian (38%), breast (32%), prostate (37%) and melanoma (32%). H...
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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
Akt/PKB is a serine/threonine kinase that promotes tumor cell growth by phosphorylating transcription factors and cell cycle proteins. There is particular interest in finding tumor-specific substrates for Akt ...