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Article
Open AccessBabesia duncani multi-omics identifies virulence factors and drug targets
Babesiosis is a malaria-like disease in humans and animals that is caused by Babesia species, which are tick-transmitted apicomplexan pathogens. Babesia duncani causes severe to lethal infection in humans, but de...
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Chapter and Conference Paper
We Chased COVID-19; Did We Forget Measles? - Public Discourse and Sentiment Analysis on Spiking Measles Cases Using Natural Language Processing
This study employs text mining and natural language processing approaches for analyzing and unearthing public discourse and sentiment toward the recent spiking Measles outbreaks reported across the globe. A de...
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Article
BSA-PEI Nanoparticle Mediated Efficient Delivery of CRISPR/Cas9 into MDA-MB-231 Cells
The discovery of bacterial-derived Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has revolutionized genome engineering and gene therapy due to its...
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Article
Open AccessThe antimalarial activity of the pantothenamide α-PanAm is via inhibition of pantothenate phosphorylation
The biosynthesis of the major acyl carrier Coenzyme A from pantothenic acid (PA) is critical for survival of Plasmodium falciparum within human erythrocytes. Accordingly, a PA analog α-PanAm showed potent activit...