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Harnessing the Power of Metallic Nanoparticles: Antimicrobial Peptide Functionalization with Gold and Silver Nanoparticles
Recent developments in nanotechnology have opened up exciting opportunities for the design of innovative antimicrobial agents. The diverse range of metallic nanoparticles, such as silver and gold, each with di...
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Article
Open AccessTick capillary feeding for the study of proteins involved in tick-pathogen interactions as potential antigens for the control of tick infestation and pathogen infection
Ticks represent a significant health risk to animals and humans due to the variety of pathogens they can transmit during feeding. The traditional use of chemicals to control ticks has serious drawbacks, includ...
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Article
Open AccessControl of tick infestations and pathogen prevalence in cattle and sheep farms vaccinated with the recombinant Subolesin-Major Surface Protein 1a chimeric antigen
Despite the use of chemical acaricides, tick infestations continue to affect animal health and production worldwide. Tick vaccines have been proposed as a cost-effective and environmentally friendly alternativ...
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Article
Open AccessGene expression profile suggests that pigs (Sus scrofa) are susceptible to Anaplasma phagocytophilum but control infection
Anaplasma phagocytophilum infects a wide variety of hosts and causes granulocytic anaplasmosis in humans, horses and dogs and tick-borne fever in ruminants. Infection with A. phagocytophilum results in the modifi...
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Article
Conservation and immunogenicity of the mosquito ortholog of the tick-protective antigen, subolesin
The control of arthropod vectors of pathogens that affect human and animal health is important for the eradication of vector-borne diseases. The ortholog of the tick-protective antigen, subolesin, was identifi...
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Article
Open AccessEvidence of the role of tick subolesin in gene expression
Subolesin is an evolutionary conserved protein that was discovered recently in Ixodes scapularis as a tick protective antigen and has a role in tick blood digestion, reproduction and development. In other organis...
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Article
Open AccessExpression of recombinant Rhipicephalus (Boophilus) microplus, R. annulatus and R. decoloratus Bm86 orthologs as secreted proteins in Pichia pastoris
Rhipicephalus (Boophilus) spp. ticks economically impact on cattle production in Africa and other tropical and subtropical regions of the world. Tick vaccines constitute a cost-effective and environmentally fr...