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Article
Open AccessSex differences in clinical presentation of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) predominantly affects women, but previous studies suggest that men with SLE present a more severe disease phenotype. In this study, we investigated a large and well-character...
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Article
Open AccessSex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms
Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and notably high female-to-male incidence ratios. Genome-...
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Article
Open AccessLong-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients
Despite men being less prone to develop autoimmune diseases, male sex has been associated with a more severe disease course in several systemic autoimmune diseases. In the present study, we aimed to investigat...
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Article
Open AccessDifference in clinical presentation between women and men in incident primary Sjögren’s syndrome
A more severe disease phenotype has been reported in men compared to women in several rheumatic diseases. However, studies have not conclusively established sex-related clinical features in primary Sjögren’s s...