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  1. Article

    Open Access

    Sex differences in clinical presentation of systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) predominantly affects women, but previous studies suggest that men with SLE present a more severe disease phenotype. In this study, we investigated a large and well-character...

    Jorge I. Ramírez Sepúlveda, Karin Bolin, Johannes Mofors in Biology of Sex Differences (2019)

  2. Article

    Open Access

    Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms

    Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and notably high female-to-male incidence ratios. Genome-...

    Magdalena Lindén, Jorge I. Ramírez Sepúlveda, Tojo James in Biology of Sex Differences (2017)

  3. Article

    Open Access

    Long-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients

    Despite men being less prone to develop autoimmune diseases, male sex has been associated with a more severe disease course in several systemic autoimmune diseases. In the present study, we aimed to investigat...

    Jorge I. Ramírez Sepúlveda, Marika Kvarnström, Per Eriksson in Biology of Sex Differences (2017)

  4. Article

    Open Access

    Difference in clinical presentation between women and men in incident primary Sjögren’s syndrome

    A more severe disease phenotype has been reported in men compared to women in several rheumatic diseases. However, studies have not conclusively established sex-related clinical features in primary Sjögren’s s...

    Jorge I. Ramírez Sepúlveda, Marika Kvarnström in Biology of Sex Differences (2017)