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Article
Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
Transcription factors are important targets for the treatment of a variety of malignancies but are extremely difficult to inhibit, as they are located in the cell's nucleus and act mainly by protein-DNA and pr...
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Article
Erratum: Id family of helix-loop-helix proteins in cancer
Nature Rev. Cancer 5, 603–615 (2005) On page 608 of this article, the statement 'latent membrane protein (LMP1, also known as TRAF3)' is incorrect. TRAF3 is the alternative name for LMP1-associated protein (LA...
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Article
Id family of helix-loop-helix proteins in cancer
Inhibitor of DNA binding (Id) family members are key regulatory proteins in a wide range of developmental and cellular processes and function by inhibiting tar...
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Article
The imprinting box of the Prader-Willi/Angelman syndrome domain
A subset of mammalian genes is monoallelically expressed in a parent-of-origin manner. These genes are subject to an imprinting process that epigenetically marks alleles according to their parental origin duri...
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Article
The imprinting box of the mouse Igf2r gene
Genomic imprinting is a phenomenon characterized by parent-of-origin-specific expression. The imprint is a mark established during germ-cell development to distinguish between the paternal and maternal copies ...