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Article
Open AccessCharacterization of different types of anxiety disorders in relation to structural integration of personality and adverse and protective childhood experiences in psychotherapy outpatients – a cross-sectional study
Current research has emphasized the role of structural integration of personality and childhood experiences for the understanding of anxiety disorders. In this study, we examined the relationship between anxie...
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Article
Open AccessHistopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients
Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC). However, manual evaluation of the diseased tissues under the microscope cannot reliably inform patient prognosis or genomic v...
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Article
Open AccessLDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma
Despite clinical advances in diagnosis and treatment, pancreatic ductal adenocarcinoma (PDAC) remains the third leading cause of cancer death, and is still associated with poor prognosis and dismal survival ra...
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Article
Open AccessSound source localization – state of the art and new inverse scheme
Acoustic source localization techniques in combination with microphone array measurements have become an important tool for noise reduction tasks. A common technique for this purpose is acoustic beamforming, w...
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Article
Open AccessNatural sleep loss is associated with lower mPFC activity during negative distracter processing
Previous research has demonstrated that loss of sleep has a negative impact on both emotional and cognitive functioning. We examined whether subjectively reported natural sleep loss is associated with the inte...
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Chapter
Clinical Information Systems in the Era of Personalized Medicine
Scientific and technical advances continue to further our understanding of how genetic alterations affect human health and the development of disease. Integrating genomic findings in the delivery of patient ca...
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Chapter
Clinical Information Systems in the Era of Personalized Medicine
Scientific and technical advances continue to further our understanding of how genetic alterations affect human health and the development of disease. Integrating genomic findings in the delivery of patient ca...
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Article
TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity
TP53INP1 is an alternatively spliced gene encoding two nuclear protein isoforms (TP53INP1α and TP53INP1β), whose transcription is activated by p53. When overexpressed, both isoforms induce cell cycle arrest in G1...
