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Open AccessStructural basis for hyperpolarization-dependent opening of human HCN1 channel
Hyperpolarization and cyclic nucleotide (HCN) activated ion channels are critical for the automaticity of action potentials in pacemaking and rhythmic electrical circuits in the human body. Unlike most voltage...
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Article
Open AccessStructural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel
Mechanosensitive channels of small conductance, found in many living organisms, open under elevated membrane tension and thus play crucial roles in biological response to mechanical stress. Amongst these chann...
