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Open AccessExercise in the Management of Metabolic-Associated Fatty Liver Disease (MAFLD) in Adults: A Position Statement from Exercise and Sport Science Australia
Metabolic-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease worldwide, affecting 25% of people globally and up to 80% of people with obesity. MAFLD is characterised by fat accu...
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Article
Patients with Nonalcoholic Steatohepatitis and Advanced Liver Disease Have the Lowest Cardiorespiratory Fitness
Cardiorespiratory fitness and liver fibrosis are independently associated with poor outcomes in patients with nonalcoholic steatohepatitis (NASH), however, conflicting reports exist about their relationship. W...
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Article
Physical Activity and Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Physical activity offers promise to protect against multiple non-hepatic primary cancers. We performed a systematic review to quantify the association between physical activity and hepatocellular carcinoma (HC...
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Article
Post-polypectomy follow-up recommendations by practicing academic gastroenterologists—does number of years in practice matter?
Colorectal cancer (CRC) is the third most deadly and fourth most common cancer worldwide. Early detection, resection, and appropriate surveillance of precursor polyps result in better outcomes. Colonoscopy is ...
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Article
Time to Step It Up: Mobile Health Intervention for Lifestyle Modification in Patients with Nonalcoholic Fatty Liver Disease
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Breaking Down Barriers to Physical Activity in Patients with Nonalcoholic Fatty Liver Disease
Lifestyle changes, including physical activity, are the cornerstones of the treatment of nonalcoholic fatty liver disease (NAFLD). For unclear reasons, most NAFLD patients do not achieve the recommended amount...
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Article
Dysplasia detection is similar between chromoendoscopy and high-definition white-light colonoscopy in inflammatory bowel disease patients: a US-matched case-control study
Inflammatory bowel disease (IBD) patients are at greater risk of develo** colorectal cancer (CRC). Detection of precursor dysplasia is important for cancer prevention. Recent guidelines recommend dye chromoe...
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Article
Exercise as Medicine: The Impact of Exercise Training on Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of global liver disease. Because current pharmacologic treatments are ineffective, lifestyle change centered on exercise remains the most effective N...
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Article
Exercise Attenuates Ribosomal Protein Six Phosphorylation in Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease worldwide. Nonalcoholic steatohepatitis (NASH), is a more severe type of NAFLD. Exercise improves NASH, by reversing steatosis, an...
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Article
Early Liver Transplantation for Severe Alcoholic Hepatitis
Although alcohol-associated liver disease has long been a major component of the liver disease landscape, it was overshadowed by chronic hepatitis C until recently. Nevertheless, with the declining incidence o...
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Article
Clinical Cirrhosis Dilemmas: Survey of Practice from the 7th International Coagulation in Liver Disease Conference
Hemostatic disorders in chronic liver disease and cirrhosis show continued expansion of research efforts. However, clinical decision making is often practiced on an individual patient level as consensus guidel...
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Article
I’m a Junior Faculty Member at an Academic Medical Center…Now What?
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Concise Commentary: The Clot Thickens—Why Pylephlebitis Is One of the Most Feared Complications of Intra-abdominal Sepsis
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Article
Management of Non-tumoral Portal Vein Thrombosis in Patients with Cirrhosis
Non-tumoral portal vein thrombosis (PVT) remains a highly relevant topic in the field of hepatology and liver transplantation with much surrounding controversy. Although multiple studies have shown that PVT is...
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Article
Hepatic Decompensation Likely Attributable to Simeprevir in Patients with Advanced Cirrhosis
Hyperbilirubinemia is a common side effect of protease inhibitors used to treat chronic hepatitis C (HCV), and most patients do not experience without clinically overt hepatotoxicity. The safety of second-wave...
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Article
Drug-Induced Liver Injury in the Elderly
Historically, the elderly have been considered to be at increased risk for drug-induced liver injury (DILI). Animal studies have demonstrated changes in hepatic physiology that affect drug metabolism in the ag...
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Article
The Safety of Same-Day Endoscopy and Percutaneous Liver Biopsy
The aim of this study was to review our experience with same-day endoscopy (SDE) plus percutaneous liver biopsy (PLB) and to evaluate its safety compared to PLB alone.