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Open AccessPlasmids in the human gut reveal neutral dispersal and recombination that is overpowered by inflammatory diseases
Plasmids are pivotal in driving bacterial evolution through horizontal gene transfer. Here, we investigated 3467 human gut microbiome samples across continents and disease states, analyzing 11,086 plasmids. Ou...
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Article
Open AccessResolving the conflict between antibiotic production and rapid growth by recognition of peptidoglycan of susceptible competitors
Microbial communities employ a variety of complex strategies to compete successfully against competitors sharing their niche, with antibiotic production being a common strategy of aggression. Here, by systemat...
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Open AccessCommunity composition of microbial microcosms follows simple assembly rules at evolutionary timescales
Managing and engineering microbial communities relies on the ability to predict their composition. While progress has been made on predicting compositions on short, ecological timescales, there is still little...
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Open AccessDeciphering functional redundancy in the human microbiome
Although the taxonomic composition of the human microbiome varies tremendously across individuals, its gene composition or functional capacity is highly conserved — implying an ecological property known as fun...
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Open AccessMortality causes universal changes in microbial community composition
All organisms are sensitive to the abiotic environment, and a deteriorating environment can cause extinction. However, survival in a multispecies community depends upon interactions, and some species may even ...
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Open AccessMap** the ecological networks of microbial communities
Map** the ecological networks of microbial communities is a necessary step toward understanding their assembly rules and predicting their temporal behavior. However, existing methods require assuming a parti...
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Universality of human microbial dynamics
A new computational method to characterize the dynamics of human-associated microbial communities is applied to data from two large-scale metagenomic studies, and suggests that gut and mouth microbiomes of hea...
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Ecology drives a global network of gene exchange connecting the human microbiome
Horizontal gene transfer — the exchange of genetic material between different species or lineages — is an important factor in bacterial evolution. A study of human microbiome data comprising more than 2,000 fu...