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  1. Article

    Open Access

    Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells

    Activation of the sympathetic nervous system causes pronounced metabolic changes that are mediated by multiple adrenergic receptor subtypes. Systemic treatment with β2-adrenergic receptor agonists results in mult...

    Jaroslawna Meister, Derek B. J. Bone, Jonas R. Knudsen… in Nature Communications (2022)

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    Exercise-Regulated Skeletal Muscle Glucose Uptake

    Muscle glucose uptake during exercise is regulated by a coordinated increase in glucose delivery (via increased blood flow and glucose moving out of the capillaries into the interstitial space), by facilitated...

    Thomas E. Jensen, Jonas R. Knudsen, Carlos Henriquez-Olguin… in Exercise Metabolism (2022)

  3. Article

    Open Access

    Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

    Reactive oxygen species (ROS) act as intracellular compartmentalized second messengers, mediating metabolic stress-adaptation. In skeletal muscle fibers, ROS have been suggested to stimulate glucose transporte...

    Carlos Henríquez-Olguin, Jonas R. Knudsen, Steffen H. Raun… in Nature Communications (2019)

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