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  1. No Access

    Article

    The Role of Deimination in Regenerative Reprogramming of Neurons

    Neurons from the adult central nervous system (CNS) demonstrate limited mRNA transport and localized protein synthesis versus develo** neurons, correlating with lower regenerative capacity. We found that dei...

    Di Ding, Mabel Enriquez-Algeciras, Anddre Osmar Valdivia… in Molecular Neurobiology (2019)

  2. No Access

    Article

    Signaling pathways leading to ischemic mitochondrial neuroprotection

    There is extensive evidence that ischemic/reperfusion mediated mitochondrial dysfunction is a major contributor to ischemic damage. However data also indicates that mild ischemic stress induces mitochondrial d...

    John W. Thompson, Srinivasan V. Narayanan… in Journal of Bioenergetics and Biomembranes (2015)

  3. No Access

    Chapter

    Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury

    Traumatic brain injury (TBI) can result in secondary ischemia. This secondary ischemic insult is implicated in post-TBI pathophysiology. Pharmacological intervention to elevate cerebral blood flow can improve ...

    Kunjan R. Dave, John W. Thompson, Jake T. Neumann… in Vascular Mechanisms in CNS Trauma (2014)

  4. No Access

    Article

    Ischemic Preconditioning Alters the Epigenetic Profile of the Brain from Ischemic Intolerance to Ischemic Tolerance

    Ischemic preconditioning is an innate neuroprotective mechanism in which a sub-injurious ischemic exposure increases the brain’s ability to withstand a subsequent, normally injurious ischemic insult. Part of i...

    John W. Thompson, Kunjan R. Dave, Juan I. Young… in Neurotherapeutics (2013)

  5. No Access

    Chapter

    Anoxia Resistance in Lower and Higher Vertebrates

    The mammalian brain has a high obligatory rate of energy consumption which renders it extremely sensitive to even brief periods of oxygen deprivation. In contrast, the crucian carp (Carassius carassius) and some ...

    John W. Thompson, Göran E. Nilsson, Miguel A. Perez-Pinzon in Innate Tolerance in the CNS (2013)

  6. No Access

    Chapter and Conference Paper

    Differential Effects of Delta and Epsilon Protein Kinase C in Modulation of Postischemic Cerebral Blood Flow

    Cerebral ischemia causes cerebral blood flow (CBF) derangements resulting in neuronal damage by enhanced protein kinase C delta (δPKC) levels leading to hippocampal and cortical neuronal death after ischemia. ...

    Hung Wen Lin, David Della-Morte, John W. Thompson… in Oxygen Transport to Tissue XXXIII (2012)

  7. No Access

    Article

    Regulation of extracellular glutamate levels in the long-term anoxic turtle striatum: coordinated activity of glutamate transporters, adenosine, K ATP + channels and GABA

    Early in anoxia the mammalian brain experiences an uncontrolled release of glutamate, which combined with the failure of glutamate reuptake mechanisms, leads to massive neurotoxic increases in extracellular gl...

    John W. Thompson, Howard M. Prentice, Peter L. Lutz in Journal of Biomedical Science (2007)

  8. No Access

    Article

    Microprocessor-based multichannel analyzer system for NaI (Tl) detectors

    A microcomputer-based multichannel analyzer system for NaI(Tl) scintillation detectors has been developed. This system simultaneously collects spectral data from two NaI(Tl) detectors, integrates spectral regi...

    Kerry J. Kelly, John W. Thompson in Journal of Radioanalytical Chemistry (1980)

  9. No Access

    Article

    Educational psychologists and animal experiments

    Stephen Wiseman has drawn attention to the gap between learning experiments with school children and experiments with rats and pigeons. However, educational psychologists such as Burt and Wiseman give little i...

    John W. Thompson in The Psychological Record (1964)

  10. No Access

    Article

    Physiological Patterns and Mental Disturbances

    THAT a diminution in the oxygen tension of the inspired air can produce mental changes is an established fact. Far less certain is the possible correlation between psychotic manifestations as seen in clinical ...

    JOHN W. THOMPSON, WM. CORWIN, J. H. ASTE-SALAZAR in Nature (1937)