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Article
Open AccessMalignant External Otitis: What the Diabetes Specialist Should Know—A Narrative Review
Malignant external otitis (MEO) is a special type of external otitis associated with extensive inflammation and osteomyelitis. It is believed to originate from the external auditory meatus and advance regional...
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Article
Open AccessThe Role of Pediatric BCG Vaccine in Type 1 Diabetes Onset
Bacille Calmette–Guérin (BCG) vaccination has shown promising therapeutic effects for type 1 diabetes (T1D). According to recent studies, immunometabolism modification and regulation of T lymphocytes constitut...
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Article
Open AccessAdherence to the National Guidelines for Follow-Up Protocol in Subjects with Type 2 Diabetes Mellitus in Greece: The GLANCE Study
Physician adherence, or lack therefore, to diabetes care and follow-up guidelines may be linked to the rates of achieving suboptimal glycaemic, blood pressure and lipid targets in people with type 2 diabetes ...
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Article
Open AccessSmartphone-Based Technology in Diabetes Management
Diabetes is a group of metabolic disorders characterized by elevated levels of blood glucose which leads over time to serious complications and significant morbidity and mortality worldwide. Self-management ta...
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Article
Open AccessInfluence of Supervised Disease Understanding and Diabetes Self-Management on Adherence to Oral Glucose-Lowering Treatment in Patients with Type 2 Diabetes
Systematic patient education has been reported to improve adherence to treatment, leading to better clinical outcomes. This cluster randomized real-world study investigated the effect of a systematic education...
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Article
Open AccessValidation of the Greek Version of the Diabetes Management Self-Efficacy Scale (GR-DMSES)
Self-efficacy has been found to have a direct relation with self-care in diabetes. Several tools have been developed and used for evaluating self-efficacy of diabetic patients, the most widely used being the D...
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Article
Sodium-Glucose Linked Transporter 2 (SGLT2) Inhibitors—Fighting Diabetes from a New Perspective
Sodium-Glucose linked transporter 2 (SGLT2) inhibitors are a new family of antidiabetic pharmaceutical agents whose action is based on the inhibition of the glucose reabsorption pathway, resulting in glucosuri...
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Chapter
Oxidative Stress in Diabetes Mellitus and Possible Interventions
A substantial amount of evidence has demonstrated that diabetes is highly associated with oxidative stress. The unifying theory that hyperglycemia-induced elevations in superoxide production underlie the activ...
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Article
Linagliptin/Metformin Fixed-Dose Combination Treatment: A Dual Attack to Type 2 Diabetes Pathophysiology
Combination therapies are a widely accepted approach to type 2 diabetes treatment, considering that monotherapies fail to provide adequate glycemic control in the majority of cases. The combination of oral ant...
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Article
Open AccessManagement of Diabetic Foot Ulcers
Diabetic foot is a serious complication of diabetes which aggravates the patient’s condition whilst also having significant socioeconomic impact. The aim of the present review is to summarize the causes and pa...
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Article
Open AccessIncretin-based therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is a progressive multisystemic disease that increases significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin resistance, beta-cell dysfunct...
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Article
Thyroid volume, selenium levels and nutritional habits in a rural region in Albania
Environmental factors are involved in goiter development. An increased number of goitrous patients were identified among outpatients in Gyrocaster, a mountainous region in Southwestern Albania. We examined pos...
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Article
DPP4 inhibitors: from sitagliptin monotherapy to the new alogliptin-pioglitazone combination therapy
Diabetes mellitus (DM) is currently considered to be an epidemic disease. A safe and effective treatment has long been sought by scientists. Incretin mimetics and dipeptidyl peptidase-4 (DPP4) inhibitors repre...
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Chapter
Endothelial Dysfunction, Inflammation, and Exercise
Vascular endothelial function is essential for the maintenance of health of the vessel wall and for the vasomotor control in both conduit and resistance vessels. These functions are due to the production of nu...
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Article
DPP4 Inhibitors: a new approach in diabetes treatment
The role of dipeptidyl peptidase-IV (DPP4) as both a regulatory enzyme and a signalling factor has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the ...