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  1. Article

    Open Access

    Malignant External Otitis: What the Diabetes Specialist Should Know—A Narrative Review

    Malignant external otitis (MEO) is a special type of external otitis associated with extensive inflammation and osteomyelitis. It is believed to originate from the external auditory meatus and advance regional...

    Christos Tsilivigkos, Konstantinos Avramidis, Eleftherios Ferekidis in Diabetes Therapy (2023)

  2. Article

    Open Access

    The Role of Pediatric BCG Vaccine in Type 1 Diabetes Onset

    Bacille Calmette–Guérin (BCG) vaccination has shown promising therapeutic effects for type 1 diabetes (T1D). According to recent studies, immunometabolism modification and regulation of T lymphocytes constitut...

    John Doupis, Konstantinos Kolokathis, Eftychia Markopoulou in Diabetes Therapy (2021)

  3. Article

    Open Access

    Adherence to the National Guidelines for Follow-Up Protocol in Subjects with Type 2 Diabetes Mellitus in Greece: The GLANCE Study

    Physician adherence, or lack therefore, to diabetes care and follow-up guidelines may be linked to the rates of achieving suboptimal glycaemic, blood pressure and lipid targets in people with type 2 diabetes ...

    Nikolaos Papanas, Moses Elisaf, Kalliopi Kotsa, Andreas Melidonis in Diabetes Therapy (2020)

  4. Article

    Open Access

    Smartphone-Based Technology in Diabetes Management

    Diabetes is a group of metabolic disorders characterized by elevated levels of blood glucose which leads over time to serious complications and significant morbidity and mortality worldwide. Self-management ta...

    John Doupis, Georgios Festas, Christos Tsilivigos, Vasiliki Efthymiou in Diabetes Therapy (2020)

  5. Article

    Open Access

    Influence of Supervised Disease Understanding and Diabetes Self-Management on Adherence to Oral Glucose-Lowering Treatment in Patients with Type 2 Diabetes

    Systematic patient education has been reported to improve adherence to treatment, leading to better clinical outcomes. This cluster randomized real-world study investigated the effect of a systematic education...

    John Doupis, Theodoros Alexandrides, Moses Elisaf, Andreas Melidonis in Diabetes Therapy (2019)

  6. Article

    Open Access

    Validation of the Greek Version of the Diabetes Management Self-Efficacy Scale (GR-DMSES)

    Self-efficacy has been found to have a direct relation with self-care in diabetes. Several tools have been developed and used for evaluating self-efficacy of diabetic patients, the most widely used being the D...

    Evaggelia Fappa, Vasiliki Efthymiou, George Landis in Advances in Therapy (2016)

  7. No Access

    Article

    Sodium-Glucose Linked Transporter 2 (SGLT2) Inhibitors—Fighting Diabetes from a New Perspective

    Sodium-Glucose linked transporter 2 (SGLT2) inhibitors are a new family of antidiabetic pharmaceutical agents whose action is based on the inhibition of the glucose reabsorption pathway, resulting in glucosuri...

    Theodoros P. Angelopoulos, John Doupis in Advances in Therapy (2014)

  8. No Access

    Chapter

    Oxidative Stress in Diabetes Mellitus and Possible Interventions

    A substantial amount of evidence has demonstrated that diabetes is highly associated with oxidative stress. The unifying theory that hyperglycemia-induced elevations in superoxide production underlie the activ...

    Triantafyllos Didangelos, John Doupis, Aristidis Veves in Studies in Diabetes (2014)

  9. No Access

    Article

    Linagliptin/Metformin Fixed-Dose Combination Treatment: A Dual Attack to Type 2 Diabetes Pathophysiology

    Combination therapies are a widely accepted approach to type 2 diabetes treatment, considering that monotherapies fail to provide adequate glycemic control in the majority of cases. The combination of oral ant...

    Chrysi Koliaki, John Doupis in Advances in Therapy (2012)

  10. Article

    Open Access

    Management of Diabetic Foot Ulcers

    Diabetic foot is a serious complication of diabetes which aggravates the patient’s condition whilst also having significant socioeconomic impact. The aim of the present review is to summarize the causes and pa...

    Kleopatra Alexiadou, John Doupis in Diabetes Therapy (2012)

  11. Article

    Open Access

    Incretin-based therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus

    Type 2 diabetes mellitus (T2DM) is a progressive multisystemic disease that increases significantly cardiovascular morbidity and mortality. It is associated with obesity, insulin resistance, beta-cell dysfunct...

    Chrysi Koliaki, John Doupis in Diabetes Therapy (2011)

  12. Article

    Thyroid volume, selenium levels and nutritional habits in a rural region in Albania

    Environmental factors are involved in goiter development. An increased number of goitrous patients were identified among outpatients in Gyrocaster, a mountainous region in Southwestern Albania. We examined pos...

    John Doupis, Charalambos Stavrianos, Katerina Saltiki, Emily Mantzou in Hormones (2009)

  13. No Access

    Article

    DPP4 inhibitors: from sitagliptin monotherapy to the new alogliptin-pioglitazone combination therapy

    Diabetes mellitus (DM) is currently considered to be an epidemic disease. A safe and effective treatment has long been sought by scientists. Incretin mimetics and dipeptidyl peptidase-4 (DPP4) inhibitors repre...

    Georgia Argyrakopoulou, John Doupis in Advances in Therapy (2009)

  14. No Access

    Chapter

    Endothelial Dysfunction, Inflammation, and Exercise

    Vascular endothelial function is essential for the maintenance of health of the vessel wall and for the vasomotor control in both conduit and resistance vessels. These functions are due to the production of nu...

    John Doupis, Jordan C. Schramm, Aristidis Veves in Diabetes and Exercise (2009)

  15. No Access

    Article

    DPP4 Inhibitors: a new approach in diabetes treatment

    The role of dipeptidyl peptidase-IV (DPP4) as both a regulatory enzyme and a signalling factor has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the ...

    John Doupis, Aristidis Veves in Advances in Therapy (2008)