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  1. Article

    Open Access

    Genomic Mosaicism of the Brain: Origin, Impact, and Utility

    Genomic mosaicism describes the phenomenon where some but not all cells within a tissue harbor unique genetic mutations. Traditionally, research focused on the impact of genomic mosaicism on clinical phenotype...

    Jared H. Graham, Johannes C. M. Schlachetzki, **aoxu Yang… in Neuroscience Bulletin (2024)

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  2. No Access

    Article

    Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson’s disease

    Mobile, sensor-based gait analysis in Parkinson’s disease (PD) facilitates the objective measurement of gait parameters in cross-sectional studies. Besides becoming outcome measures for clinical studies, the a...

    Franz Marxreiter, Heiko Gaßner, Olga Borozdina, Jens Barth… in Journal of Neurology (2018)

  3. No Access

    Article

    α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy

    Multiple system atrophy (MSA) is a rare atypical parkinsonian disorder characterized by a rapidly progressing clinical course and at present without any efficient therapy. Neuropathologically, myelin loss and ...

    Benjamin Ettle, Bilal E. Kerman, Elvira Valera, Clarissa Gillmann… in Acta Neuropathologica (2016)

  4. Article

    Open Access

    Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?

    Oligodendrocytes, the myelinating cells of the central nervous system, mediate rapid action potential conduction and provide trophic support for axonal as well as neuronal maintenance. Their progenitor cell po...

    Benjamin Ettle, Johannes C. M. Schlachetzki, Jürgen Winkler in Molecular Neurobiology (2016)

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