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Article
Open AccessGenomic Mosaicism of the Brain: Origin, Impact, and Utility
Genomic mosaicism describes the phenomenon where some but not all cells within a tissue harbor unique genetic mutations. Traditionally, research focused on the impact of genomic mosaicism on clinical phenotype...
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Article
Open AccessOligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?
Oligodendrocytes, the myelinating cells of the central nervous system, mediate rapid action potential conduction and provide trophic support for axonal as well as neuronal maintenance. Their progenitor cell po...