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4 Result(s)

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  1. No Access

    Article

    Ligand-dependent localization and function of ORP–VAP complexes at membrane contact sites

    Oxysterol-binding protein/OSBP-related proteins (ORPs) constitute a conserved family of sterol/phospholipid-binding proteins with lipid transporter or sensor functions. We investigated the spatial occurrence a...

    Marion Weber-Boyvat, Henriikka Kentala… in Cellular and Molecular Life Sciences (2015)

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    Protocol

    Kinetic Activation of Rab8 Guanine Nucleotide Exchange Factor Rabin8 by Rab11

    The Rab family of small GTPases acts as molecular switches that control various stages of vesicular transport. Rab8 functions in exocytic trafficking from the trans-Golgi network (TGN) and recycling endosomes to ...

    Shanshan Feng, Bin Wu, Johan Peränen, Wei Guo in Rab GTPases (2015)

  3. No Access

    Article

    Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures

    A previously uncharacterized member of the I-BAR subfamily of BAR-domain proteins, Pinkbar, is expressed in epithelial cells, where it stabilizes planar membrane sheets. Structural, biochemical and mutagenesis...

    Anette Pykäläinen, Malgorzata Boczkowska… in Nature Structural & Molecular Biology (2011)

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    Article

    1H, 13C and 15N resonance assignments of the human mesencephalic astrocyte-derived neurotrophic factor

    Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease, where dopaminergic cells die most prominently in the area of substantia nigra. Neurotrophic factors (NTFs) are secreted proteins, w...

    Maarit Hellman, Johan Peränen, Mart Saarma, Perttu Permi in Biomolecular NMR Assignments (2010)