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  1. Article

    Open Access

    Statistical analysis plan for the replacing protein via enteral nutrition in a stepwise approach in critically ill patients (REPLENISH) randomized clinical trial

    The optimal amount and timing of protein intake in critically ill patients are unknown. REPLENISH (Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients) trial evaluates whe...

    Yaseen M Arabi, Hasan M. Al-Dorzi, Omar Aldibaasi, Musharaf Sadat, Jesna Jose in Trials (2024)

  2. Article

    Open Access

    Replacing protein via enteral nutrition in a stepwise approach in critically ill patients: the REPLENISH randomized clinical trial protocol

    Protein intake is recommended in critically ill patients to mitigate the negative effects of critical illness-induced catabolism and muscle wasting. However, the optimal dose of enteral protein remains unknown...

    Yaseen M. Arabi, Hasan M. Al-Dorzi, Musharaf Sadat, Dina Muharib, Haifa Algethamy in Trials (2023)

  3. Article

    Open Access

    P55 Remote Ischaemic Preconditioning Reduces Cardiac Biomarkers During Vascular Surgery

    The primary aim of this study was to evaluate the effects of remote ischaemic preconditioning (RIPC) on preventing the leakage of cardiac damage biomarkers in patients undergoing vascular surgery.

    Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer in Artery Research (2019)

  4. Article

    Open Access

    Genetic variants in humanin nuclear isoform gene regions show no association with coronary artery disease

    Coronary artery disease contributes to noncommunicable disease deaths worldwide. In order to make preventive methods more accurate, we need to know more about the development and progress of this pathology, in...

    Mall Eltermaa, Maili Jakobson, Meeme Utt, Sulev Kõks, Reedik Mägi in BMC Research Notes (2019)

  5. Article

    Open Access

    P65 Remote Ischaemic Preconditioning Reduces Kidney Injury in Vascular Surgery

    Perioperative acute kidney injury has been found to occur in 12% of patients undergoing lower limb revascularisation (Arora et al., 2013). The aim of the current double-blinded, randomised and shamcontrolled p...

    Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer in Artery Research (2018)

  6. Article

    Open Access

    Effects of 60 minutes of hyperoxia followed by normoxia before coronary artery bypass grafting on the inflammatory response profile and myocardial injury

    Ischemic preconditioning induces tolerance against ischemia-reperfusion injury prior a sustained ischemic insult. In experimental studies, exposure to hyperoxia for a limited time before ischemia induces a low...

    Inga Karu, Peeter Tähepõld, Arno Ruusalepp in Journal of Negative Results in BioMedicine (2012)