5 Result(s)
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Joel M. Chick
Science, Humanities and Social Sciences, multidisciplinary
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Article
Author Correction: Defining the consequences of genetic variation on a proteome-wide scale
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Article
Open AccessAge-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes
Glaucoma is a chronic disease that shares many similarities with other neurodegenerative disorders of the central nervous system. This study was designed to evaluate the association between glaucoma and other ...
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Article
The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival
The cyclin D3–CDK6 kinase complex, which is overactive in some cancers, inhibits two key glycolysis enzymes and thereby enhances the levels of antioxidants in cells, promoting tumour cell survival.
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Article
Defining the consequences of genetic variation on a proteome-wide scale
Genetic variation modulates protein expression through both transcriptional and post-transcriptional mechanisms. To characterize the consequences of natural genetic diversity on the proteome, here we combine a...
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Article
Open AccessInduction of virulence factors in Giardia duodenalis independent of host attachment
Giardia duodenalis is responsible for the majority of parasitic gastroenteritis in humans worldwide. Host-parasite interaction models in vitro provide insights into disease and virulence and help us to understand...
