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  1. Article

    Open Access

    Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

    A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H2) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H2 has a salutary effect ...

    Kazuhisa Sugai, Tomoyoshi Tamura, Motoaki Sano, Shizuka Uemura in Scientific Reports (2020)

  2. Article

    Open Access

    A Dipeptidyl Peptidase-4 Inhibitor, Teneligliptin, Decreases Plasma Triglyceride-Rich Lipoprotein Remnants in Diabetic Patients with Chronic Kidney Disease Undergoing Hemodialysis

    A high plasma level of remnant-like particle cholesterol (RLP-C), which is equivalent to triglyceride-rich lipoprotein remnant, is an important coronary risk marker. RLP-C level is high, independent of other p...

    Koichiro Homma, Joe Yoshizawa, Yutaka Shiina, Hideki Ozawa, Muneki Igarashi in Drugs in R&D (2017)

  3. Article

    Open Access

    Increase of electronegative-LDL-fraction ratio and IDL-cholesterol in chronic kidney disease patients with hemodialysis treatment

    It is known that the increased level of IDL and oxidized LDL are associated with risk of cardiovascular disease, and the lipoprotein abnormalities accelerate atherosclerosis. Cardiovascular disease is a major ...

    Yuji Hirowatari, Yasuhiko Homma, Joe Yoshizawa in Lipids in Health and Disease (2012)