Skip to main content

10 Result(s)

within Joe Craft Remove this filter Immunology Remove this filter

and

  1. No Access

    Article

    IL-27 gives a good gut feeling about immune regulation

    Regulatory T (Treg) cells maintain the balance between immune protection and pathology. Research has now found that intestinal Treg cells produce IL-27 to restrain TH17 cell-mediated immune responses, effectively...

    Emily R. Siniscalco, Joe Craft in Nature Immunology (2023)

  2. No Access

    Article

    TFH cells progressively differentiate to regulate the germinal center response

    Craft and colleagues show that follicular helper T cells progress through transcriptionally and functionally distinct stages that provide specific signals for germinal center regulation.

    Jason S Weinstein, Edward I Herman, Begoña Lainez, Paula Licona-Limón… in Nature Immunology (2016)

  3. No Access

    Article

    Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells

    The precise factors that control effective memory formation by T cells are unclear. Kaech et al. demonstrate that regulatory T cell–produced IL-10 is critical for the generation of CD8+ memory cells.

    Brian J Laidlaw, Weiguo Cui, Robert A Amezquita, Simon M Gray… in Nature Immunology (2015)

  4. No Access

    Article

    PTENtiating autoimmunity through Treg cell deregulation

    Regulatory T cells require the phosphatase PTEN to maintain suppressive function in homeostatic conditions through preserved expression of CD25 and the transcription factor Foxp3.

    John P Ray, Joe Craft in Nature Immunology (2015)

  5. Article

    Correction: Corrigendum: Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation

    Nat. Immunol. 10, 1125–1132 (2009); published online 6 September 2009; corrected after print 5 October 2009 In the version of this article initially published, two relevant papers are not cited. The following ...

    Benjamin R Marks, Heba N Nowyhed, **-Young Choi, Amanda C Poholek… in Nature Immunology (2010)

    Download PDF (107 KB) View Article

  6. No Access

    Article

    Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation

    Several unconventional T cell populations, including γδ T cells and regulatory T cells, are selected by recognition of self antigen in the thymus. Craft and colleagues add TH-17 cells to the list of T cell subset...

    Benjamin R Marks, Heba N Nowyhed, **-Young Choi, Amanda C Poholek… in Nature Immunology (2009)

  7. No Access

    Article

    Resistance to Development of Collagen-Induced Arthritis in C57BL/6 Mice Is Due to a Defect in Secondary, but Not in Primary, Immune Response

    Collagen-induced arthritis (CIA) is a rodent model of human rheumatoid arthritis. Mice of the H-2q (DBA/1J) background are highly susceptible to disease whereas mice of the H-2b (C57BL/6, B6) background are resis...

    Meng Pan, Insoo Kang, Joe Craft, Zhinan Yin in Journal of Clinical Immunology (2004)

  8. No Access

    Article

    γδ T cells in autoimmunity

    γδ T cells likely play a critical role in the host defenses, and recent evidence has indicated they are important in regulation of the immune response after pathogen challenge. Data are also accumulating that ...

    Zhinan Yin, Joe Craft in Springer Seminars in Immunopathology (2000)

  9. No Access

    Article

    Autoreactive T cells in murine lupus

    The conventional paradigm to explain systemic lupus erythematosus (SLE) is that disease results from tissue deposition of pathogenic autoantibodies and immune complexes, secondary to activation of autoreactive...

    Joe Craft, Stanford Peng, Takao Fujii, Masato Okada… in Immunologic Research (1999)

  10. No Access

    Chapter

    Lessons from Knockout and Transgenic Lupus-Prone Mice

    Inbred mice have provided the majority of knowledge regarding the pathogenesis of lupus. Their ease of use relates predominately to their more accessible immune organs, greater genetic homogeneity, and more pr...

    Stanford L. Peng, Joe Craft in Lupus (1999)