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Article
Open AccessOvarian carcinoma in children with constitutional mutation of SMARCA4: single-family report and literature review
Ovarian carcinoma is an extremely rare malignancy in children, often develo** on the underlying inherited background. Female carriers of pathogenic germline mutations of SMARCA4 are at risk of an aggressive typ...
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Article
Open AccessResults of two consecutive treatment protocols in Polish children with acute lymphoblastic leukemia
The aim of the study was to retrospectively compare the effectiveness of the ALL IC-BFM 2002 and ALL IC-BFM 2009 protocols and the distribution of risk groups by the two protocols after minimal residual diseas...
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Article
Open AccessFeasibility of diffusion-weighted imaging with DWIBS in staging Hodgkin lymphoma in pediatric patients: comparison with PET/CT
The aim of the study was to evaluate feasibility of diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) method in diagnosing Hodgkin lymphoma in pediatric patients and to comp...
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Article
What are the true volumes of SEGA tumors? Reliability of planimetric and popular semi-automated image segmentation methods
To evaluate the reliability of the standard planimetric methodology of volumetric analysis and three different open-source semi-automated approaches of brain tumor segmentation.
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Article
Open AccessAbnormal serum microRNA profiles in tuberous sclerosis are normalized during treatment with everolimus: possible clinical implications
Tuberous sclerosis (TSC) is a monogenic disease resulting from defects of the TSC1 or TSC2 genes, which encode the proteins forming hamartin-tuberin tumor suppressor complex, the mammalian target of rapamycin com...
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Article
Everolimus treatment among patients with tuberous sclerosis affects serum lipid profile
The purpose of the study was to evaluate lipid homeostasis before and after treatment of everolimus, the mammalian target of the rapamycin (mTOR) inhibitor, among patients with tuberous sclerosis complex (TSC).
