7 Result(s)
within
Jiwu Chen
Science, Humanities and Social Sciences, multidisciplinary
English
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Article
Open AccessDifferential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells
Proteasome activity is frequently enhanced in cancer to accelerate metastasis and tumorigenesis. REGγ, a proteasome activator known to promote p53/p21/p16 degradation, is often overexpressed in cancer cells. H...
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Article
Open AccessLarge-scale identification of encystment-related proteins and genes in Pseudourostyla cristata
The transformation of a ciliate into cyst is an advance strategy against an adverse situation. However, the molecular mechanism for the encystation of free-living ciliates is poorly understood. A large-scale i...
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Article
Open AccessCorrection: Corrigendum: Large-scale identification of encystment-related proteins and genes in Pseudourostyla cristata
The transformation of a ciliate into cyst is an advance strategy against an adverse situation. However, the molecular mechanism for the encystation of free-living ciliates is poorly understood. A large-scale i...
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Article
Open AccessThe REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
Increasing incidence of inflammatory bowel disorders demands a better understanding of the molecular mechanisms underlying its multifactorial aetiology. Here we demonstrate that mice deficient for REGγ, a prot...
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Article
Open AccessNew contribution to the morphology and molecular mechanism of Euplotes encysticus encystment
Ciliated protists are a large group of single-cell eukaryotes, leading to the resting cysts in unfavorable environmental condition. However, the underlying molecular mechanism of encystment in the free-living ...
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Article
Open AccessNovel insights into molecular mechanisms of Pseudourostyla cristata encystment using comparative transcriptomics
The encystment of many ciliates is an advanced survival strategy against adversity and the most important reason for ciliates existence worldwide. However, the molecular mechanism for the encystment of free-li...
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Article
Open AccessTranscriptome analysis reveals the encystment-related lncRNA expression profile and coexpressed mRNAs in Pseudourostyla cristata
Ciliated protozoans form dormant cysts for survival under adverse conditions. The molecular mechanisms regulating this process are critical for understanding how single-celled eukaryotes adapt to the environme...
