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  1. Article

    Open Access

    ZBTB12 is a molecular barrier to dedifferentiation in human pluripotent stem cells

    Development is generally viewed as one-way traffic of cell state transition from primitive to developmentally advanced states. However, molecular mechanisms that ensure the unidirectional transition of cell fa...

    Dasol Han, Guo**g Liu, Yujeong Oh, Seyoun Oh, Seungbok Yang… in Nature Communications (2023)

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  2. Article

    Open Access

    The Role of Chromatin Density in Cell Population Heterogeneity during Stem Cell Differentiation

    We incorporate three-dimensional (3D) conformation of chromosome (Hi-C) and single-cell RNA sequencing data together with discrete stochastic simulation, to explore the role of chromatin reorganization in dete...

    Mahdi Golkaram, Jiwon Jang, Stefan Hellander, Kenneth S. Kosik… in Scientific Reports (2017)

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