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Open AccessMethylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology
Preventing tau aggregation is a potential therapeutic strategy in Alzheimer’s disease and other tauopathies. Recently, liquid–liquid phase separation has been found to facilitate the formation of pathogenic ta...
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Open AccessErratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
Nature Communications 8 Article number:14632 (2017); Published: 8 March 2017; Updated: 31 March 2017 The original version of this Article contained an error in the spelling of post-transcriptional in the title...
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Article
Open AccessPARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
Poly(ADP-ribosyl)ation (PARylation) is mainly catalysed by poly-ADP-ribose polymerase 1 (PARP1), whose role in gene transcription modulation has been well established. Here we show that, in response to LPS exp...
