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Article
Retrospective evaluation of neonates with fatal congenital lung malformation: A single center 15-year forensic autopsy experience
Congenital lung malformation (CLM) is a leading cause of infant mortality. Clinical methods for diagnosing CLM mainly rely on computed tomography, magnetic resonance imaging, ultrasonography, and Doppler. Howe...
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Article
Internal validation of the GA118-24B Genetic Analyzer, a stable capillary electrophoresis system for forensic DNA identification
The GA118-24B Genetic Analyzer (hereafter, “GA118-24B”) is an independently developed capillary electrophoresis instrument. In the present research, we designed a series of validation experiments to test its p...
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Article
Research on the Potential Biomarkers of Mild Traumatic Brain Injury: a Systematic Review and Bibliometric Analysis
Reliable diagnostic methods for mild traumatic brain injury (mTBI) are lacking, and many researchers continue to search for objective biomarkers that can both define and detect mTBI. Although much research has...
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Article
Analysis of the risk of traumatic brain injury and evaluation neurogranin and myelin basic protein as potential biomarkers of traumatic brain injury in postmortem examination
In forensic pathology, traumatic brain injury (TBI) is a frequently encountered cause of death. Unfortunately, the statistic autopsy data, risk investigation about injury patterns, and circumstances of TBI are...
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Article
Development and validation of novel 8-dye short tandem repeat multiplex system for forensic applications
DNA profiling of short tandem repeats (STRs) is the primary method for genoty** forensic samples. However, degraded DNA and trace samples are still major problems for commercial 5- or 6-dye STR kits. In orde...
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Article
Open AccessDynamic transcriptome profiling exploring cold tolerance in forensically important blow fly, Aldrichina grahami (Diptera: Calliphoridae)
Aldrichina grahami (Diptera: Calliphoridae) is a forensically important fly, which has been widely applied to practical legal investigations. Unlike other necrophagous flies, A. grahami exhibits cold tolerance wh...
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Article
Bacteria-targeting BSA-stabilized SiC nanoparticles as a fluorescent nanoprobe for forensic identification of saliva
Forensic saliva identification represents an increasingly useful auxiliary means of crime investigations, particularly in sex crimes. Salivary bacteria detection techniques have been shown to be viable methods...
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Article
Potential use of high-throughput sequencing of bacterial communities for postmortem submersion interval estimation
Microorganisms play vital roles in the natural decomposition of carcasses in aquatic systems. Using high-throughput sequencing techniques, we evaluated the composition and succession of microbial communities t...
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Article
Open AccessFungal succession during mammalian cadaver decomposition and potential forensic implications
The necrobiome is the postmortem community that includes bacteria, fungi, arthropods, and other cadaver-associated organisms. It has been suggested as biological evidence for forensic investigation. Fungi form...
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Article
Accuracy of the Demirjian and Willems methods of dental age estimation for children from central southern China
The aim of this study was to compare the accuracy of the Demirjian method and the Demirjian method as revised by Willems for age estimation based on orthopantomograms from central southern Chinese Han populati...
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Article
Rapid and sensitive detection of ketamine in blood using novel fluorescence genosensor
In recent years, drug abuse has been considered as a most challenging social problem that aroused public attention. Ketamine has increased in unregulated use as a ‘recreational drug’ in teenagers. However, the...
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Article
Open AccessA rapid evaluation of acute hydrogen sulfide poisoning in blood based on DNA-Cu/Ag nanocluster fluorescence probe
Hydrogen sulfide (H2S) is a highly toxic gas as a cause of inhalational death. Accurate detection of H2S poisoning concentration is valuable and vital for forensic workers to estimate the cause of death. But so f...
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Article
Open AccessEstimation of postmortem interval by vitreous potassium evaluation with a novel fluorescence aptasensor
Estimation of postmortem interval (PMI) is a central role in medico-legal identification. Analysis of vitreous potassium ions (K+) concentration is frequently used by forensic workers to estimate PMI. This paper ...
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Article
Open AccessA high-throughput fluorimetric microarray with enhanced fluorescence and suppressed “coffee-ring” effects for the detection of calcium ions in blood
A rapid, ultrasensitive, and high-throughput fluorimetric microarray method has been developed using hydrophobic pattern as the microarray substrate and 3-aminopropyltriethoxysilane-coupled carboxylic acid cal...
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Article
Genetic polymorphisms of 26 Y-STR loci in the Mongolian minority from Horqin district, China
To study the population data of Y chromosome STR (Y-STRs) of the Mongolian minority population residing in the Horqin district, we analyzed haplotypes of 26 Y-STRs (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390,...
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Article
Open AccessPotential use of bacterial community succession for estimating post-mortem interval as revealed by high-throughput sequencing
Decomposition is a complex process involving the interaction of both biotic and abiotic factors. Microbes play a critical role in the process of carrion decomposition. In this study, we analysed bacterial comm...
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Article
Open AccessParallel Analysis of 124 Universal SNPs for Human Identification by Targeted Semiconductor Sequencing
SNPs, abundant in human genome with lower mutation rate, are attractive to genetic application like forensic, anthropological and evolutionary studies. Universal SNPs showing little allelic frequency variation...
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Article
Open AccessPopulation genetic study of 34 X-Chromosome markers in 5 main ethnic groups of China
As a multi-ethnic country, China has some indigenous population groups which vary in culture and social customs, perhaps as a result of geographic isolation and different traditions. However, upon close intera...
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Article
Identification of forensically important sarcophagid flies (Diptera: Sarcophagidae) in China based on COI and period gene
Unequivocal identification of insect specimens is an essential requirement in forensic entomology. With the development of molecular identification, spate of discussions about the feature of the DNA fragments ...
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Article
Molecular characterization and expression pattern of an odorant receptor from the myiasis-causing blowfly, Lucilia sericata (Diptera: Calliphoridae)
The blowfly Lucilia sericata (Diptera: Calliphoridae) is a facultative ectoparasite that causes myiasis in both man and animals, leading to serious human health problems and economic losses in the livestock indus...
