204 Result(s)

Article

Comparison of microscopic full-laminectomy (open surgery) and microendoscopic minimally invasive hemilaminectomy for thoracic extramedullary spinal tumours

Minimally invasive treatments for spinal cord tumours are common. The aim of this study was to compare the perioperative outcomes of patients with thoracic extramedullary spinal tumours (TEST) treated by micro...

Gang Chen, Yong Yu, Chengxing Qian, Yong Jiang… in Journal of Cardiothoracic Surgery (2024)

Article

Effectiveness and pregnancy outcomes of ultrasound-indicated and physical examination-indicated cervical cerclage: a retrospective study from a single centre

Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide, and cervical incompetence (CIC) is a significant contribution. Cervical cerclage (CC) is an effective obstetric intervent...

Linxiang Huang, Wenting Wang, Yuchuan Wang, Jie Chen… in BMC Pregnancy and Childbirth (2024)

Article

Cai’s herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response

This study investigates the therapeutic mechanisms of Cai’s Herbal Tea in Type 1 Diabetes Mellitus (T1DM) mice, focusing on its effects on mitochondrial change and autophagy via the AMP-activated protein kinas...

Hongchun Li, Yanfei Gao, Mengdi Li, Yue Dong, Jie Chen, Bingyue Zhang… in Acta Diabetologica (2024)

Article

A controlled study of the hygienic technical evaluation of the transaxillary approach for inflation-free single-port lumpectomy versus conventional transcervical anterior open surgery in radical thyroid cancer resection

To evaluate sanitary techniques for radical thyroid cancer surgery via the transaxillary approach without inflation single-port endoscopic surgery (TAWISES) and the conventional open anterior cervical approach...

Jie Chen, Bo Xu BM, Chaojie Zhang BM, Chengquan Ma… in World Journal of Surgical Oncology (2024)

Article

The efficacy and assessment value of the level of thyroglobulin wash-out after fine-needle aspiration cytodiagnosis in the evaluation of lymph node metastasis in papillary thyroid carcinoma

The purpose of this study was to evaluate the efficacy and clinical value of US, FNAC,FNA-Tg and FNAC + FNA-Tg, as well as the cutoff values of FNA-Tg to evaluate LN metastasis.

Jie Chen, Zongwu Lin, Bo Xu, Tianwen Lu… in World Journal of Surgical Oncology (2024)

Article

Analysis of PD-L1 promoter methylation combined with immunogenic context in pancreatic ductal adenocarcinoma

Despite the successful application of programmed cell death ligand 1 (PD-L1)-blocking strategies in some types of cancers and well-established prognostic indicators in pancreatic ductal adenocarcinoma (PDAC), ...

**nyuan Chen, Shuangni Yu, Jie Chen, **anlong Chen in Cancer Immunology, Immunotherapy (2024)

Article

Structure–activity relationships of the intramolecular disulphide bonds in LEAP2, an antimicrobial peptide from Acrossocheilus fasciatus

The liver-expressed antimicrobial peptide 2 (LEAP2) plays a pivotal role in the host’s immune response against pathogenic microorganisms. Numerous such antimicrobial peptides have recently been shown to mitiga...

Ci-Gang Yu, Li Ma, Di-Ni Zhang, Yue Ma, Chang-Yong Wang… in BMC Veterinary Research (2024)

Article

Application of AI-assisted MRI for the identification of surgical target areas in pediatric hip and periarticular infections

To develop an AI-assisted MRI model to identify surgical target areas in pediatric hip and periarticular infections.

Yuwen Liu, Lingyu Chen, Mingjie Fan, Tao Zhang, Jie Chen… in BMC Musculoskeletal Disorders (2024)

Article

Apparent diffusion coefficient and tissue stiffness are associated with different tumor microenvironment features of hepatocellular carcinoma

To investigate associations between tissue diffusion, stiffness, and different tumor microenvironment features in resected hepatocellular carcinoma (HCC).

Jie Chen, Zhenru Wu, Zhen Zhang, Yidi Chen, Meng Yin… in European Radiology (2024)

Article

Publisher Correction: Chlamydia psittaci Pneumonia in a patient with motor neuron disease: a case report

Huade Luo, Lingling Jiang, Jie Chen, Dongying Wang… in BMC Infectious Diseases (2024)

Article

An esculentin-1 homolog from a dark-spotted frog (Pelophylax nigromaculatus) possesses antibacterial and immunoregulatory properties

Esculentin-1, initially discovered in the skin secretions of pool frogs (Pelophylax lessonae), has demonstrated broad-spectrum antimicrobial activity; however, its immunomodulatory properties have received little...

Jie Chen, Ci-Gang Yu, Min-Min Zhou, Gao-Jian Zhang, Hai-Long Su… in BMC Veterinary Research (2024)

Article

Seronegative primary Sjögren’s syndrome, a distinct subtype of primary Sjögren’s syndrome in Chinese patients

To investigate the clinical and immune characteristics of patients with primary Sjögren’s syndrome (pSS) who were negative for anti–Sjögren’s-syndrome-related antigen A antibodies (anti-SSA) and anti–Sjögren’s...

**gying Lan, Chaoqiong Deng, Heqing Huang, Peishi Rao, Yangchun Chen… in BMC Rheumatology (2024)

Article

Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53

Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 1 diabetes mellitus (T1DM), which still lacks adequate therapy. Irisin, a cleavage peptide off fibronectin type III domain-containi...

Yuan-juan Tang, Zhen Zhang, Tong Yan, Ken Chen, Guo-fan Xu… in Cardiovascular Diabetology (2024)

Article

The influence of WeChat education and care program on anxiety, depression, insomnia, and general state of health in parents of pediatric acute lymphoblastic leukemia patients

WeChat-based education and care program serves as a promising nursing method for relieving mental stress in parents of pediatric patients. This study purposed to explore the influence of the WeChat education a...

Hui Duan, Li Wang, Hui Li, Zhongyu Wang… in Journal of Cancer Research and Clinical On… (2024)

Article

Multimodal digital assessment of depression with actigraphy and app in Hong Kong Chinese

There is an emerging potential for digital assessment of depression. In this study, Chinese patients with major depressive disorder (MDD) and controls underwent a week of multimodal measurement including actig...

Jie Chen, Ngan Yin Chan, Chun-Tung Li, Joey W. Y. Chan… in Translational Psychiatry (2024)

Article

Prognostic impacts of repeated sepsis in intensive care unit on autoimmune disease patients: a retrospective cohort study

Autoimmune diseases (ADs) may be complicated by sepsis when intensive care unit (ICU) admission. But repeated sepsis among AD patients has not been studied yet. The aim of this study is to investigate the impa...

**ming Yang, Jie Chen, Min Zhang, Qingsa Zhou, Bing Yan in BMC Infectious Diseases (2024)

Article

Prediction of late recurrence after curative-intent resection using MRI-measured spleen volume in patients with hepatocellular carcinoma and cirrhosis

Late recurrence of hepatocellular carcinoma (HCC) after liver resection is regarded as a de novo tumor primarily related to the severity of underlying liver disease. We aimed to investigate risk factors, espec...

Chongtu Yang, Jia Tan, Yidi Chen, Yanshu Wang, Yali Qu, Jie Chen… in Insights into Imaging (2024)

Article

AKT2^S128/CCTα^S315/319/323-positive cancer-associated fibroblasts (CAFs) mediate focal adhesion kinase (FAK) inhibitors resistance via secreting phosphatidylcholines (PCs)

Abnormal metabolism is regarded as an oncogenic hallmark related to tumor progression and therapeutic resistance. Present study employed multi-omics, including phosphoproteomics, untargeted metabolomics and li...

Jie Chen, Lingyuan Zhang, Yuheng Zhu, Di Zhao… in Signal Transduction and Targeted Therapy (2024)

Article

Human papillomavirus E7 protein induces homologous recombination defects and PARPi sensitivity

Cervical cancer is a common gynecological malignancy, pathologically associated with persistent infection of high-risk types of human papillomavirus (HPV). Previous studies revealed that HPV-positive cervical ...

Siqi He, Ao Wang, **g Wang, Zizhi Tang… in Journal of Cancer Research and Clinical On… (2024)

Article

Circ_0027885 sponges miR-203-3p to regulate RUNX2 expression and alleviates osteoporosis progression

Osteoporosis (OP) is a progressive metabolic disorder that is difficult to cure clinically. The molecular mechanisms of OP urgently need to be further examined. This study was designed to explore the potential...

Shuhua Fang, Dingwen Cao, Zhanpo Wu, Jie Chen, Yafei Huang… in BMC Musculoskeletal Disorders (2024)