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Open AccessProfound hypoxemia and hypotension during posterior spinal fusion in a spinal muscular atrophy child with severe scoliosis: a case report
Anesthesia for spinal muscular atrophy (SMA) patients undergoing spinal deformity surgery is challenging. We report an unusual case of an SMA girl who developed severe intraoperative hypoxemia and hypotension ...
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Open AccessMorphological analysis of isolated hemivertebra: radiographic manifestations related to the severity of congenital scoliosis
The natural history of congenital scoliosis (CS) caused by hemivertebra varies greatly. This study aimed to explore the association between the morphology of hemivertebra and the severity of CS, since the diag...
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Open AccessUnilateral interlaminar fenestration on the convex side provides a reliable access for intrathecal administration of nusinersen in spinal muscular atrophy: a retrospective study
As the first gene therapy for spinal muscular atrophy (SMA), nusinersen is supposed to be administrated via intrathecal injection regularly for a lifetime. However, for SMA patients with severe spinal deformit...
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Open AccessA large pedigree study confirmed the CGG repeat expansion of RILPL1 Is associated with oculopharyngodistal myopathy
Oculopharyngodistal myopathy (OPDM) is an autosomal dominant adult-onset degenerative muscle disorder characterized by ptosis, ophthalmoplegia and weakness of the facial, pharyngeal and limb muscles. Trinucleo...
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Correction to: DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer
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Open AccessEffects of physiotherapeutic scoliosis-specific exercise in patients with mild juvenile scoliosis
A combined retrospective and prospective analysis on the therapeutic effect of physiotherapeutic scoliosis-specific exercise (PSSE) in mild juvenile idiopathic scoliosis (JIS) patients.
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Open AccessApical region correction and global balance: a 3-rods surgical strategy for the treatment of severe and rigid scoliosis
The treatment of severe and rigid scoliosis is challenging. We developed a surgical strategy for severe and rigid scoliosis since 2014. This study aimed to retrospectively analyze the safety and efficacy of ap...
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Open AccessRisk factors of postoperative pulmonary complications after primary posterior fusion and hemivertebra resection in congenital scoliosis patients younger than 10 years old: a retrospective study
Postoperative pulmonary complications are common and associated with morbidity and mortality. Congenital scoliosis is a failure of vertebral formation and/or segmentation arising from abnormal vertebral develo...
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Open AccessOlder fusion-surgery age in congenital scoliosis patients is a risk factor for extended length of stay, more estimated blood loss, longer fused segments and higher medical costs: a retrospective study
Contradictory opinions about whether early correction and fusion surgeries should be performed for congenital scoliosis (CS) patients at a young age exist. The objectives of this study were to analyze the asso...
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Open AccessCombined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial
To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TX...
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Open AccessFactors and predictive model associated with perioperative complications after long fusion in the treatment of adult non-degenerative scoliosis
Adult non-degenerative scoliosis accounts for 90% of spinal deformities in young adults. However, perioperative complications and related risk factors of long posterior instrumentation and fusion for the treat...
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Article
Miller Fisher syndrome associated with COVID-19: an up-to-date systematic review
Recently, during the pandemic infection of the novel SARS-CoV-2, some cases of Miller Fisher syndrome (MFS) have been reported. We want to summarize the main features of patients with MFS and COVID-19. A PubMe...
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Open AccessGrowing-rod implantation improves nutrition status of early-onset scoliosis patients: a case series study of minimum 3-year follow-up
Early onset scoliosis (EOS) may cause malnutrition in affected patients. Growing-rod treatment has been an effective protocol for treating EOS. The objective of this study is to demonstrate whether growing-rod...
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Open AccessComparison between surgical fusion and the growing-rod technique for early-onset neurofibromatosis type-1 dystrophic scoliosis
Spinal deformities constitute one of the most common types of manifestations of neurofibromatosis type-1 (NF-1), which can lead to either dystrophic or non-dystrophic early-onset scoliosis (EOS). Surgical trea...
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Open AccessPosterior only instrumented fusion provides incomplete curve control for early-onset scoliosis in type 1 neurofibromatosis
The mid-long term outcomes of posterior spinal fusion in pediatric neurofibromatosis type 1 (NF-1) patients are rarely reported, so does the effectiveness of itsorthopeidc maintenance function. This study aims...
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Open AccessPredictors for blood loss in pediatric patients younger than 10 years old undergoing primary posterior hemivertebra resection: a retrospective study
Blood loss during hemivertebra resection may be substantial. Few studies have examined the risk factors of blood loss undergoing hemivertebra resection, especially those in patients under 10 years old.
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Open AccessMental health of patients with adolescent idiopathic scoliosis and their parents in China: a cross-sectional survey
Adolescent idiopathic scoliosis (AIS) is an adolescent onset spinal deformity, which can negatively affect the mental health of these patients. But no studies about their parental mental health have been repor...
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Open AccessKyphoscoliosis with Klippel-Trenaunay syndrome: a case report and literature review
Klippel-Trenaunay syndrome (KTS) is a rare congenital syndrome characterized by the triad of venous varicosities, capillary malformations and limb hypertrophy. However, KTS may rarely occur in combination with...
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Thoracic Spinal Deformities Affected Cardiopulmonary Function in Patients with Scoliosis
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Comparison of Cardiopulmonary Function in Patients with Congenital Scoliosis and Adolescent Idiopathic Scoliosis