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Article
Alteration of gut microbiota in Henoch-Schönlein purpura children with gastrointestinal involvement
The compositional and structural changes of gut microbiota were closely related to the status of Henoch–Schönlein purpura (HSP).
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Article
The Assessment of Practice Quality–Mindfulness (PQ-M): Translation and Psychometric Properties in Chinese Population
The practice quality of mindfulness is a key factor associated with the effects of mindfulness interventions, and it can be assessed using the Practice Quality–Mindfulness (PQ-M) questionnaire. The English-ver...
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Article
Open AccessPrediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study
Spinal cord injury (SCI) is a prevalent and serious complication among patients with spinal tuberculosis (STB) that can lead to motor and sensory impairment and potentially paraplegia. This research aims to id...
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Article
Open AccessEffect of early preventive supplementation with calcium and phosphorus on metabolic bone disease in premature infants
The objective was to study the effect of early preventive calcium and phosphorus supplementation on metabolic bone disease in preterm infants.
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Article
Study on the Inhibitory Activity of Benzo[d]imidazo[2,1-b]thiazole Compounds Containing Chromone in Lung Cancer Cells
In recent years, lung cancer has become one of the most common malignant tumors in the world, which seriously threatens the life and health of mankind. Lung cancer is also the most common cancer in China. Acco...
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Article
Robust channel estimation based on the maximum entropy principle
Channel estimation (CE) is one of the crucial and fundamental elements of signal processing, especially considering the requirement of high accuracy in future wireless communication systems. Most traditional C...
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Article
Do Mindfulness-Based Interventions Reduce Burnout of College Students in China? A Randomized Controlled Trial
There is an increasing recognition of mindfulness-based interventions (MBIs) as a promising way to reduce burnout. However, inconsistent results were found on the effect among college students. In addition, th...
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Open AccessAccuracy of the spontaneous breathing trial using a combined CPAP + PSV model to predict extubation outcomes in very preterm infants
Very preterm infants often require mechanical ventilation. However, objective criteria to predict the outcomes of extubation in very premature neonates remain lacking. The aim of this study was to investigate ...
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Article
Open AccessEffect of growth hormone therapy on liver enzyme and other cardiometabolic risk factors in boys with obesity and nonalcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) has become the most common causes of liver disease in children and adolescents. Although several reports have confirmed the significant correlation between NAFLD and g...
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Article
Open AccessSTAT3 and SPI1, may lead to the immune system dysregulation and heterotopic ossification in ankylosing spondylitis
This study was aimed to identify the biomarkers for diagnosis and reveal the immune microenvironment changes in ankylosing spondylitis (AS).
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Article
Open AccessTYROBP, TLR4 and ITGAM regulated macrophages polarization and immune checkpoints expression in osteosarcoma
We established a relationship among the immune-related genes, tumor-infiltrating immune cells (TIICs), and immune checkpoints in patients with osteosarcoma. The gene expression data for osteosarcoma were downl...
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Article
Open AccessIs there a correlation between upper lumbar disc herniation and multifidus muscle degeneration? A retrospective study of MRI morphology
The purpose of the study is to investigate the correlation between upper lumbar disc herniation (ULDH) and multifidus muscle degeneration via the comparison of width, the cross-sectional area and degree of fat...
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Article
Matching vacancy formation energy and defect levels with the density of amorphous Ga2O3
In this study, we present six structural models for amorphous Ga2O3 (a-Ga2O3) with different mass densities from ab initio molecular dynamics simulations. The detailed local structural order, non-perfect coordina...
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Article
Open AccessMediating effects of depressive symptoms on social support and quality of life among rural older Chinese
It is not well clear how psychosocial factors like depressive symptoms, social support affect quality of life in rural elderly in China. This study aimed to investigate the mediating role of depressive symptom...
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Article
Mild hyperamylasemia in type 1 diabetic children without diabetic ketoacidosis is associated with C-peptide
The aim of this study is to investigate the relationship between plasma amylase concentration and C-peptide level in type 1 diabetic and healthy children.
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Article
Bifidobacterium and Lactobacillus for preventing necrotizing enterocolitis in very-low-birth-weight preterm infants: a systematic review and meta-analysis
The therapeutic effect of Bifidobacterium and Lactobacillus on necrotizing enterocolitis (NEC) in very-low-birth-weight preterm infants was controversial, and we aimed to explore the exact impact of the two probi...
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Article
Open AccessMetformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway
The aim of our study was to determine the effect of metformin administration on juvenile type 1 diabetes mellitus and atherosclerosis in apolipoprotein E null (ApoE−/−) mice and to explore the mechanism involved.
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Article
Neuroprotective and anti-inflammatory effects of isoliquiritigenin in kainic acid-induced epileptic rats via the TLR4/MYD88 signaling pathway
Epileptogenesis is a complex pathological process that occurs after an initial brain injury and involves a series of molecular events. Isoliquiritigenin (ISL), a flavonoid in licorice, is reported to have anti...
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Article
Open AccessIsoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity
Oxidative stress and neuroinflammation are central pathogenic mechanisms common to many neurological diseases. Isoliquiritigenin (ISL) is a flavonoid in licorice with multiple pharmacological properties, inclu...
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Article
Open AccessNon-invasive high-frequency oscillatory ventilation versus nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome: Study protocol for a multi-center prospective randomized controlled trial
Invasive mechanical ventilation (IMV) is associated with the development of adverse pulmonary and non-pulmonary outcomes in very premature infants. Various modes of non-invasive respiratory support are increas...