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Article
Polymorphisms of chemokine receptors and its ligand alleles influencing genetic susceptibity to HIV-1 infection in eight ethnic groups in Chinese mainland
Limited genetic information is available concerning the polymorphisms of HIV-1 resistant genes in indigenous Chinese populations. The aim of this study is to identify the allelic frequencies of the chemokine and ...
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Chapter and Conference Paper
Two-Pattern Strings
This paper introduces a new class of strings on {a, b}, called two-pattern strings, that constitute a substantial generalization of Sturmian strings while at the same time sharing many of their nice properties. I...
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Chapter and Conference Paper
The Reuse Study of Small Agricultural Machinery’s Product Information Model
It is estimated that more than 90% of industrial design activity is based on variant design. How to use the product information model of similar products and to improve design efficiency and the designer’s cre...
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Chapter and Conference Paper
Axiomatic Design Using Ontology Modeling for Interoperability in Small Agriculture Machinery Product Development
Small Agricultural machinery (SAM) is applied widely in agriculture, forestry and stockbreeding. We focus the reconfiguration and Interoperability of the complex process of SAM product development, and propose...
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Article
Long term effect of methylparathion contamination on soil microbial community diversity estimated by 16S rRNA gene cloning
The long-term effects of methylparathion contamination on the diversity of soil microbial community was investigated by a culture-independent approach using small subunit ribosomal RNA (SSU rRNA) gene-based cl...
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Article
Cloning of the organophosphorus pesticide hydrolase gene clusters of seven degradative bacteria isolated from a methyl parathion contaminated site and evidence of their horizontal gene transfer
Seven organophosphorus pesticide-degrading bacteria harboring the methyl parathion degrading (mpd) gene were isolated from a methyl parathion contaminated site. In this study, the 4.7 kb mpd gene cluster, conserv...
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Article
Simultaneous biodegradation of methyl parathion and carbofuran by a genetically engineered microorganism constructed by mini-Tn5 transposon
A genetically engineered microorganism (GEM) capable of simultaneous degrading methyl parathion (MP) and carbofuran was successfully constructed by random insertion of a methyl parathion hydrolase gene (mpd) into...
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Article
Degradation of methamidophos by Hyphomicrobium species MAP-1 and the biochemical degradation pathway
Methamidophos is one of the most widely used organophosphorus insecticides usually detectable in the environment. A facultative methylotroph, Hyphomicrobium sp. MAP-1, capable of high efficiently degrading metham...
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Article
Hydrolytic Dechlorination of Chlorothalonil by Ochrobactrum sp. CTN-11 Isolated from a Chlorothalonil-Contaminated Soil
A bacterial strain, designated as CTN-11, capable of degrading chlorothalonil (CTN), was isolated from a chlorothalonil-contaminated soil in China. Based on the morphological, biochemical characteristics and c...
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Article
Open AccessThe cellular source for APOBEC3G's incorporation into HIV-1
Human APOBEC3G (hA3G) has been identified as a cellular inhibitor of HIV-1 infectivity. Viral incorporation of hA3G is an essential step for its antiviral activity. Although the mechanism underlying hA3G virio...
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Article
Identification of the Biochemical Degradation Pathway of Triazophos and its Intermediate in Diaphorobacter sp. TPD-1
Triazophos is one of the most widely used organophosphorus insecticides usually detectable in the environment. A bacterial strain, Diaphorobacter sp. TPD-1, capable of using triazophos and its intermediate, 1-phe...
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Article
Open AccessRetraction Note: the cellular source for APOBEC3G's incorporation into HIV-1
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Article
An isofenphos-methyl hydrolase (Imh) capable of hydrolyzing the P–O–Z moiety of organophosphorus pesticides containing an aryl or heterocyclic group
Organophosphorus pesticide (OP) hydrolases play key roles in the degradation and decontamination of agricultural and household OPs and in the detoxification of chemical warfare agents. In this study, an isofen...
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Article
Identification of anti-tuberculosis agents that target the cell-division protein FtsZ
Antibiotic resistance to Mycobacterium tuberculosis is a growing problem. Therefore, development of new anti-tuberculosis antibiotics is urgent for the control of tuberculosis (TB) infections. FtsZ, the homolog o...
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Article
Open AccessFormononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE2 expression
The activation of ERK, p38 and JNK signal cascade in host cells has been demonstrated to up-regulate of enterovirus 71 (EV71)-induced cyclooxygenase-2 (COX-2)/ prostaglandins E2 (PGE2) expression which is essenti...
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Article
Open AccessLearning from berberine: Treating chronic diseases through multiple targets
Although advances have been made, chemotherapy for chronic, multifactorial diseases such as cancers, Alzheimer’s disease, cardiovascular diseases and diabetes is far from satisfactory. Agents with different me...
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Article
Open AccessDesign, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition
Lycorine is reported to be a multifunctional compound. We previously showed that lycorine is an HCV inhibitor with strong activity. Further research on the antivirus mechanism indicated that lycorine does not ...
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Article
Reductive dehalogenation of 3,5-dibromo-4-hydroxybenzoate by an aerobic strain of Delftia sp. EOB-17
To confirm the reductive dehalogenation ability of the aerobic strain of Delftia sp. EOB-17, finding more evidences to support the hypothesis that reductive dehalogenation may occur extensively in aerobic bacteri...
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Article
At-Source Control of Freight Rail Noise: A Case Study
Controlling freight rail noise at-source can be more effective than seeking to treat either the noise path or the receiver. This paper presents a framework for at-source noise control of freight rail noise. Th...
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Article
Open AccessLipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease
We recently demonstrated a positive effect of berberine on nonalcoholic fatty liver disease patients after 16 weeks of treatment by comparing mere lifestyle intervention in type 2 diabetes patients with berber...
