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  1. Article

    Open Access

    Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate

    Adipogenesis has an important role in regulating energy homeostasis in mammals. 3T3-L1 preadipocytes have been widely used as an in vitro model for analyzing the molecular mechanism of adipogenesis. Previous repo...

    Wei Guo, Jiangnan Chen, Ying Yang, Jianbei Zhu, Jiarui Wu in Cell Death & Disease (2016)

  2. Article

    Bcl-2 cleavages at two adjacent sites by different caspases promote cisplatin-induced apoptosis

    The protein encoded by bcl-2 proto-oncogene plays an important role in the mitochondria-mediated apoptotic pathway. Although the general role of Bcl-2 is anti-apoptotic, previous work showed that Bcl-2 fragments ...

    Jianbei Zhu, Ying Yang, Jiarui Wu in Cell Research (2007)