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Article
Open AccessEpigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate
Adipogenesis has an important role in regulating energy homeostasis in mammals. 3T3-L1 preadipocytes have been widely used as an in vitro model for analyzing the molecular mechanism of adipogenesis. Previous repo...
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Article
In-plane nonlinear buckling of circular arches including shear deformations
A numerical strategy is presented to trace the pre-buckling as well as the post-buckling nonlinear equilibrium paths for elastic circular arches in which the effects of shear deformations and the geometric non...
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Article
In-plane buckling of prismatic funicular arches with shear deformations
The in-plane buckling behavior of funicular arches is investigated numerically in this paper. A finite strain Timoshenko beam-type formulation that incorporates shear deformations is developed for generic funi...
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Article
In-plane buckling of circular arches and rings with shear deformations
A finite strain formulation is developed for elastic circular arches and rings in which the effects of shear deformations are included. Timoshenko beam hypothesis is adopted for incorporating shear. Finite str...
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Article
Bcl-2 cleavages at two adjacent sites by different caspases promote cisplatin-induced apoptosis
The protein encoded by bcl-2 proto-oncogene plays an important role in the mitochondria-mediated apoptotic pathway. Although the general role of Bcl-2 is anti-apoptotic, previous work showed that Bcl-2 fragments ...