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    Methotrexate-mediated inhibition of RAD51 expression and homologous recombination in cancer cells

    Methotrexate is an inhibitor of folic acid metabolism. Homologous recombination is one of the most important ways to repair double-stranded breaks in DNA and influence the radio- and chemosensitivity of tumor ...

    Li-Qing Du, **ao-Qing Du, Jian-Qiang Bai… in Journal of Cancer Research and Clinical On… (2012)