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  1. No Access

    Article

    TRAF3/STAT6 axis regulates macrophage polarization and tumor progression

    Converting tumor-associated macrophages (TAMs) from the M2 to the M1 phenotype is considered an effective strategy for cancer therapy. TRAF3 is known to regulate NF-κB signaling. However, the role of TRAF3 in ...

    Jian-Hong Shi, Li-Na Liu, Dan-Dan Song, Wen-Wen Liu… in Cell Death & Differentiation (2023)

  2. Article

    Open Access

    TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

    TRK-fused gene (TFG) is known to be involved in protein secretion and plays essential roles in an antiviral innate immune response. However, its function in LPS-induced inflammation and pyroptotic cell death i...

    Jian-Hong Shi, Chen Ling, Ting-Ting Wang, Li-Nuo Zhang, Wen-Wen Liu… in Cell Death & Disease (2022)

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  3. Article

    Open Access

    Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma

    CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study,...

    Liang Ding, Yalei Wen, **n Zhang, Fang Zhao, Kenao Lv… in Cell Death Discovery (2021)

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