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TRAF3/STAT6 axis regulates macrophage polarization and tumor progression

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  1. Article

    Open Access

    Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma

    CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study,...

    Liang Ding, Yalei Wen, **n Zhang, Fang Zhao, Kenao Lv… in Cell Death Discovery (2021)

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  2. Article

    Open Access

    TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

    TRK-fused gene (TFG) is known to be involved in protein secretion and plays essential roles in an antiviral innate immune response. However, its function in LPS-induced inflammation and pyroptotic cell death i...

    Jian-Hong Shi, Chen Ling, Ting-Ting Wang, Li-Nuo Zhang, Wen-Wen Liu… in Cell Death & Disease (2022)

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