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  1. No Access

    Article

    Transgenic plants expressing two Bacillus thuringiensis toxins delay insect resistance evolution

    Preventing insect pests from develo** resistance to Bacillus thuringiensis (Bt) toxins produced by transgenic crops is a major challenge for agriculture. Theoretical models suggest that plants containing two di...

    Jian-Zhou Zhao, Jun Cao, Yaxin Li, Hilda L Collins, Richard T Roush… in Nature Biotechnology (2003)

  2. No Access

    Article

    Site-specific DNA excision in transgenic rice with a cell-permeable Cre recombinase

    The removal of selected marker genes from transgenic plants is necessary to address biosafety concerns and to carry out further experiments with transgenic organisms. In the present study, the 12-amino-acid me...

    Ming-**a Cao, Jian-Qiu Huang, Quan-Hong Yao, Sheng-Jun Liu… in Molecular Biotechnology (2006)

  3. No Access

    Article

    Bacillus thuringiensis protein production, signal transduction, and insect control in chemically inducible PR-1a/cry1Ab broccoli plants

    In an effort to develop a chemically inducible system for insect management, we studied production of Cry1Ab Bacillus thuringiensis (Bt) protein and control of the diamondback moth (DBM), Plutella xylostella L., ...

    Jun Cao, Sarah L. Bates, Jian-Zhou Zhao, Anthony M. Shelton… in Plant Cell Reports (2006)

  4. No Access

    Article

    Effects of additives on efficiency and specificity of ligase detection reaction

    Ligase detection reaction (LDR) is adaptable to a wide variety of applications ranging from scientific research to clinical diagnosis, especially in the field of nucleotide polymorphism discrimination and anal...

    Zhen-**an **ao, Hui-Min Cao, **ao-Hui Luan, Jian-Long Zhao… in Molecular Biotechnology (2007)

  5. No Access

    Article

    A Feasible and Quantitative Encoding Method for Microbeads with Multicolor Quantum Dots

    Multicolor encoded beads were achieved by incorporating two color core-shell quantum dots (QDs) (CdSe/ZnS) to commercial polystyrene (PS) beads. By controlling the concentration ratios of the two quantum dots ...

    Hai-Qiao Wang, Zhen-Li Huang, Tian-Cai Liu, Jian-Hao Wang… in Journal of Fluorescence (2007)

  6. No Access

    Article

    Building the sequence map of the human pan-genome

    Here we integrate the de novo assembly of an Asian and an African genome with the NCBI reference human genome, as a step toward constructing the human pan-genome. We identified ∼5 Mb of novel sequences not presen...

    Ruiqiang Li, Yingrui Li, Hancheng Zheng, Ruibang Luo, Hongmei Zhu… in Nature Biotechnology (2010)

  7. No Access

    Article

    An optimized RNA amplification method for prokaryotic expression profiling analysis

    DNA microarray technology has been extensively used for gene expression analysis of both eukaryotic and prokaryotic organisms. For eukaryotic gene expression profiling, the poly(A)-based reverse transcription ...

    Feng-Lin Cao, Han-Hua Liu, Ya-Hui Wang, Yu Liu… in Applied Microbiology and Biotechnology (2010)

  8. Article

    Open Access

    Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential

    Completion of genome sequences for the diploid Setaria italica reveals features of C4 photosynthesis that could enable improvement of the polyploid biofuel crop switchgrass (Panicum virgatum). The genetic basis o...

    Gengyun Zhang, **n Liu, Zhiwu Quan, Shifeng Cheng, Xun Xu… in Nature Biotechnology (2012)

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  9. No Access

    Article

    Identification and molecular cytology analysis of cold tolerance introgression lines derived from Oryza sativa L. mating with O. rufipogon Griff.

    A previously constructed introgression lines (ILs) population including 239 lines was used to evaluate the cold-tolerant ability. The ILs with strong cold tolerance which were identified in the present study w...

    **ang-Dong Luo, Liang-Fang Dai, Juan-Fang Cao, Shui-Rong Jian, Ya-Ling Chen… in Euphytica (2012)

  10. No Access

    Article

    Synthesis, Characterization, Optical Properties and Theoretical Studies of Novel Substituted Imidazo[1,5-a]pyridinyl 1,3,4-Oxadiazole Derivatives

    Novel imidazo[1,5-a]pyridinyl 1,3,4-Oxadiazole derivatives were synthesized and characterised by IR, 1H NMR and HRMS.UV-vis absorption and fluorescence properties of these compounds in different solutions showed ...

    Yan-Qing Ge, Teng Wang, Gui Yun Duan, Li Hua Dong, **ao Qun Cao… in Journal of Fluorescence (2012)

  11. No Access

    Chapter

    Implications: Societal Collective Outcomes, Including Manufacturing

    The convergences in advanced science and engineering interconnect with a number of core social issues that include the arrangement of means and modes of production and the associated labor skill requirements, ...

    Jian Cao, Michael A. Meador… in Convergence of Knowledge, Technology and S… (2013)

  12. No Access

    Chapter

    Methods to Improve and Expedite Convergence

    Whereas the R&D process of convergence of knowledge and technology has been largely reactive or coincidental in the past, there is a growing realization among the world’s scientific communities that to take be...

    Mihail C. Roco, George Whitesides… in Convergence of Knowledge, Technology and S… (2013)

  13. No Access

    Article

    Arginine aminopeptidase from white shrimp (Litopenaeus vannamei) muscle: purification and characterization

    Aminopeptidases act on N-terminal of proteins and peptides produce free amino acids making an impact on the final flavor of foods. An arginine aminopeptidase (RAP) which preferred to hydrolyze basic amino acid...

    Ling Zhang, Qiu-Feng Cai, Guo-** Wu… in European Food Research and Technology (2013)

  14. No Access

    Article

    Musca Domestica Larva Lectin Induces Apoptosis in BEL-7402 Cells Through a Ca2+/JNK-mediated Mitochondrial Pathway

    Although Musca domestica larvae lectin (MLL) is able to inhibit cancer cell proliferation and to induce cancer cell apoptosis, the molecular mechanism(s) responsible for these processes remain elusive. In the ...

    Chun-Ling Wang, Yan **a, Jian-Zeng Nie, Minghui Zhou… in Cell Biochemistry and Biophysics (2013)

  15. No Access

    Article

    Synthesis of S-adenosyl-L-methionine in Escherichia coli

    Abstract S-adenosyl-L-methionine (SAM) is an important physiological metabolite in vivo and may be useful in medicines. SAM is produced from L-methionine and ATP catalyzed by S-adenosyl-L-methionine synthetase (S...

    **ao-Nan Wei, Min-Jie Cao, Jian Li, Huan Li… in Biotechnology and Bioprocess Engineering (2014)

  16. No Access

    Article

    Effects of Chromium Methionine Supplementation on Growth Performance, Serum Metabolites, Endocrine Parameters, Antioxidant Status, and Immune Traits in Growing Pigs

    The effects of dietary chromium methionine (CrMet) on growth performance, serum metabolites, endocrine parameters, antioxidant status, and immune traits in growing pigs were investigated. A total of 180 crossb...

    Yao-Yao Tian, Li-Ying Zhang, Bing Dong, Jun Cao… in Biological Trace Element Research (2014)

  17. No Access

    Article

    Purification and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from abalone (Haliotis discus hannai Ino) gonads

    Abalone gonads were hydrolyzed using alcalase followed by papain to produce angiotensin I-converting enzyme (ACE) inhibitory peptides. Gel filtration column chromatography analysis showed that the molecular we...

    Qiang Wu, Qiu-Feng Cai, Zhi-Peng Tao, Le-Chang Sun… in European Food Research and Technology (2015)

  18. No Access

    Article

    Enzymatic transformation of vina-ginsenoside R7 to rare notoginsenoside ST-4 using a new recombinant glycoside hydrolase from Herpetosiphon aurantiacus

    An eco-friendly and convenient preparation method for notoginsenoside ST-4 has been established by completely transforming vina-ginsenoside R7 using a recombinant glycosidase hydrolyzing enzyme (HaGH03) from Herp...

    Ru-Feng Wang, Ming-Min Zheng, Yue-De Cao, Hao Li… in Applied Microbiology and Biotechnology (2015)

  19. Article

    Open Access

    Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement

    Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.

    Tianzhen Zhang, Yan Hu, Wenkai Jiang, Lei Fang, Xueying Guan… in Nature Biotechnology (2015)

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  20. No Access

    Article

    Effect of Dietary Selenomethionine Supplementation on Growth Performance, Tissue Se Concentration, and Blood Glutathione Peroxidase Activity in Kid Boer Goats

    We used 240 kid Boer goats that were divided into six groups. The control group was fed a basal diet containing 0.05 mg of selenium (Se)/kg dry matter (DM). Trial groups received the basal diet supplemented wi...

    Yu-xuan Song, **-xing Hou, Lei Zhang, Jian-gang Wang… in Biological Trace Element Research (2015)

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