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Article
Open AccessSingle-cell and genome-wide Mendelian randomization identifies causative genes for gout
Gout is a prevalent manifestation of metabolic osteoarthritis induced by elevated blood uric acid levels. The purpose of this study was to investigate the mechanisms of gene expression regulation in gout disea...
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Article
Open AccessDisulfidptosis decoded: a journey through cell death mysteries, regulatory networks, disease paradigms and future directions
Cell death is an important part of the life cycle, serving as a foundation for both the orderly development and the maintenance of physiological equilibrium within organisms. This process is fundamental, as it...
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Article
Preparation of NiMoO4 porous nanosheets by freezing method as adhesive-free electrodes for high-performance flexible supercapacitors
This article successfully prepared porous NiMoO4 sheet-like structured nanomaterials deposited on carbon cloth using the freeze-drying method. The morphology and phase structure were characterized by SEM, TEM, an...
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Article
Open AccessEpigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury
Spinal cord injury (SCI) is a severe neurological disorder that causes neurological impairment and disability. Neural stem/progenitor cells (NS/PCs) derived from induced pluripotent stem cells (iPSCs) represen...
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Article
Magnetic flux leakage, eddy current loss and temperature distribution for large scale winding in UHVDC converter transformer based on equivalent 2D axisymmetric model
Temperature distribution is an important index that reflects the safe operation ability of power transformers. In this paper, finite element simulation is used to study the magnetic field, loss, and temperatur...
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Chapter and Conference Paper
Thermal Aging State Evaluation Method for Submarine Cable Insulation Based on High-Voltage Frequency Domain Dielectric Characteristic Quantity
The cross-linked polyethylene (XLPE) is widely used in the insulation of the seam cable because it has good electrical performance, mechanical performance and heat resistance, and it is the basis for ensuring ...
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Chapter and Conference Paper
Study on Amplitude Characteristics of Electromagnetic and Vibration Parameters for “Plug-in” Type High-Voltage Conductor Connection Structures in GIS
The “plug” type high-voltage conductor connection structures is extremely prone to parts loosening under frequent action, its connection reliability will be drastically reduced under continuous mechanical vibr...
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Chapter and Conference Paper
Dynamic Behavior of Suspended Bubbles in Insulating Oil Correlation with Flow Field Distribution
In recent years, arcing faults inside large oil-immersed power transformers have been frequent. Suspended bubbles, as the main product of high temperature, high humidity, material aging and cracking gas produc...
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Chapter and Conference Paper
Field Ionization Degree Influence on Discharge Streamer of Natural Ester Based on Ionization Energy Calculation Under Changing Electric Field
During the development of streamer discharge in transformer oil, field ionization is considered to be the main ionization mechanism that causes liquid dielectric streamer breakdown. With the change of the dist...
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Chapter and Conference Paper
Lightning Impulse Breakdown Behavior of Three-Element Mixed Insulating Oil Under Long Oil Gap and Its Weibull Model Analysis
The lightning impulse breakdown (LIB) characteristics of three-element mixed insulating oil (T-EMO) under long oil gap are crucial to the structural design of T-EMO transformer with high voltage level. The LIB...
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Chapter and Conference Paper
Research on Gas Diffusion Behavior in Three-Element Mixed Insulation Oil-Paper Composite System
The gas information in oil-immersed transformers is an important parameter in the identification of the insulation condition Three-element mixed insulation oil is a new type of insulating liquid, which has bee...
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Chapter and Conference Paper
Analysis of Vibration Characteristics of Mechanical Defects in GIS Three-Position Switch Travel not in Place Based on Multi-point Information
Mechanical defects in the travel of three-position switches not in place are an important factor in the failure of GIS equipment and a serious threat to grid security. In order to realise the effective operati...
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Article
Heart rate, perceived stress and prosocial behaviour: real-time psychophysiological correlates of prosocial behaviour
Physiological studies of prosocial behaviour have indicated an association between resting heart rate variability and prosocial behaviour. Little is known about whether real-time heart rate in prosocial behavi...
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Article
Open AccessUnit-cell-thick zeolitic imidazolate framework films for membrane application
Zeolitic imidazolate frameworks (ZIFs) are a subset of metal–organic frameworks with more than 200 characterized crystalline and amorphous networks made of divalent transition metal centres (for example, Zn2+ and...
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Article
Conversion of Coal into Graphitized Microcrystalline Carbon with a Hierarchical Porous Structure for Electrochemical Hydrogen Storage
Electrochemical hydrogen storage, which can be performed at ambient temperatures and mild pressures, is regarded as a promising technique to store hydrogen safely and efficiently. In this study, the electroche...
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Article
Engineering of an ene-reductase for producing the key intermediate of antiepileptic drug Brivaracetam
(R)-4-Propyldihydrofuran-2(3H)-one (R-PDFO) is the key chiral intermediate for the antiepileptic drug Brivaracetam. Lacking a simple and economical method to approaching R-PDFO, the production of R-PDFO also rema...
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Article
Open AccessCharacterization and applications of evoked responses during epidural electrical stimulation
Epidural electrical stimulation (EES) of the spinal cord has been FDA approved and used therapeutically for decades. However, there is still not a clear understanding of the local neural substrates and consequ...
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Article
Preparation of ZnCo2O4 porous nano-flower-like materials by one-step cryogenic hydrothermal method and study on their capacitive and photocatalytic properties
In this paper, the porous nano-flower structures were successfully constructed on carbon cloth (CC) substrate by a simple one-step cryogenic hydrothermal method. The morphology and phase analysis showed that t...
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Article
Tanshinone IIA promotes apoptosis by downregulating BCL2 and upregulating TP53 in triple-negative breast cancer
Tanshinone IIA (Tan IIA) was mainly used for cardiovascular disease treatment. Recent studies have demonstrated the role of Tan IIA for tumor treatment, but its mechanism remains unclear. At the first, the inh...
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Article
Why are we unwilling to help sometimes? Reconsideration and integration of the attribution-affect model and the arousal: cost-reward model
Hel** is a virtue, but people are unwilling to help sometimes. The present study reconsidered and integrated the attribution-affect model and the arousal: cost-reward model to reveal decisive factors in the ...
