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Chapter and Conference Paper
Rapid Determination of Compound Rifampicin Tablets Using Near Infrared Spectroscopy with Artificial Neural Network
This paper has investigated the application of near infrared (NIR) spectroscopy with artificial neural network (ANN) for synchronous and rapid determination of rifampicin, isoniazid and pyrazinamide in compoun...
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Chapter and Conference Paper
Artificial Intelligence Based Optimization of Fermentation Medium for β-Glucosidase Production from Newly Isolated Strain Tolypocladium Cylindrosporum
A Tolypocladium cylindrosporum strain was isolated for efficiently produce extracellular thermoacidophilic β-glucosidase (BGL). This objective of the present paper is to integrate two different artificial intelli...
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Article
Preparation and the antitumor activity in vitro of polysaccharides from Tricholoma matsutake
Tricholoma matsutake is the most valuable mushroom exhibiting a characteristic and delicate flavor as well as several biological activities among the various mushroom species. Extraction procedure and antitumor a...
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Article
Perceiving and Interacting Affordances: A New Model of Human–Affordance Interactions
This article introduces a new affordance framework for humans and human design. Based on previous important concepts in product design–affordance, signifier, and product semantics, the authors propose three ne...
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Article
A New Method for Computed Tomography Angiography (CTA) Imaging via Wavelet Decomposition-Dependented Edge Matching Interpolation
The interpolation technique of computed tomography angiography (CTA) image provides the ability for 3D reconstruction, as well as reduces the detect cost and the amount of radiation. However, most of the image...
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Article
18β-Glycyrrhetinic Acid, a Novel Naturally Derived Agent, Suppresses Prolactin Hyperactivity and Reduces Antipsychotic-Induced Hyperprolactinemia in In Vitro and In Vivo Models
The purpose of this study was to examine the effects of 18β-glycyrrhetinic acid (GA), a novel naturally derived agent, in suppressing prolactin (PRL) hyperactivity and reducing antipsychotic-induced hyperprol...
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Chapter and Conference Paper
Message Franking via Committing Authenticated Encryption
We initiate the study of message franking, recently introduced in Facebook’s end-to-end encrypted message system. It targets verifiable reporting of abusive messages to Facebook without compromising security g...
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Article
Open AccessIL-33/ST2 plays a critical role in endothelial cell activation and microglia-mediated neuroinflammation modulation
Interleukin-33 (IL-33) is increasingly being recognized as a key immunomodulatory cytokine in many neurological diseases.
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Article
Open AccessSarcodon imbricatus polysaccharides improve mouse hematopoietic function after cyclophosphamide-induced damage via G-CSF mediated JAK2/STAT3 pathway
Sarcodon imbricatus, a rare medicinal and edible fungus, has various pharmacological bioactivities. We investigated the effects of S. imbricatus polysaccharides (SIPS) on hematopoietic function and identified the...
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Article
Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
The normally soluble TAR DNA-binding protein 43 (TDP-43) is found aggregated both in reversible stress granules and in irreversible pathogenic amyloid. In TDP-43, the low-complexity domain (LCD) is believed to...
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Article
Open AccessA Convenient Non-harm Cervical Spondylosis Intelligent Identity method based on Machine Learning
Cervical spondylosis (CS), a most common orthopedic diseases, is mainly identified by the doctor’s judgment from the clinical symptoms and cervical change provided by expensive instruments in hospital. Owing t...
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Article
Author Correction: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
The Pro-Apoptotic Activity of Tamarixetin on Liver Cancer Cells Via Regulation Mitochondrial Apoptotic Pathway
Based on the various pharmacological activities of tamarixetin, the present study investigated the cytotoxicity property of tamarixetin in human liver cancer cells including PLC/PRF/5 and HepG2 cells, and thei...
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Chapter and Conference Paper
First Place Solution of PAKDD Cup 2020
In this paper, we will describe our solution to the PAKDD Cup 2020 Alibaba intelligent operation and maintenance algorithm competition. The biggest challenge of this competition is how to model this problem. I...
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Article
Studies on the Neuroprotection of Osthole on Glutamate-Induced Apoptotic Cells and an Alzheimer’s Disease Mouse Model via Modulation Oxidative Stress
In the present study, the neuroprotection of osthole (OST) was confirmed. In l-glutamic acid (l-Glu)-damaged HT22 cells, a 3-h pre-incubation with OST-enhanced cell viability suppressed the apoptosis rate; inhibi...
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Article
Open AccessTemporal and textual analysis of social media on collective discourses during the Zika virus pandemic
While existing studies have investigated the role of social media on health-related communication, little is known about the potential differences between different users groups on different social media platf...
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Article
Open AccessCryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid
hnRNPA2 is a human ribonucleoprotein (RNP) involved in RNA metabolism. It forms fibrils both under cellular stress and in mutated form in neurodegenerative conditions. Previous work established that the C-term...
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Article
Open AccessA decade of antimicrobial resistance research in social science fields: a scientometric review
Though social sciences are expectedly instrumental in combating antimicrobial resistance (AMR), their research on AMR has been historically lacking.
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Chapter and Conference Paper
Efficient Generic Arithmetic for KKW
Katz et al., CCS 2018 (KKW) is a popular and efficient MPC-in-the-head non-interactive ZKP (NIZK) scheme, which is the technical core of the post-quantum signature scheme Picnic, currently considered for stand...
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Article
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Amyloidosis of human islet amyloid polypeptide (hIAPP) is a pathological hallmark of type II diabetes (T2D), an epidemic afflicting nearly 10% of the world’s population. To visualize disease-relevant hIAPP fib...
