![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessMicrofluidics-enabled fluorinated assembly of EGCG-ligands-siTOX nanoparticles for synergetic tumor cells and exhausted t cells regulation in cancer immunotherapy
Immune checkpoint inhibitor (ICI)-derived evolution offers a versatile means of develo** novel immunotherapies that targets programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) axis. However, one majo...
-
Chapter and Conference Paper
Effect of Promoter G-quadruplex on Gene Expression and Its Interaction with Transcription Factor
G-quadruplexes (G4s) are special nucleic acid structures widely found in human genome. They are enriched in important regions such as telomeres and promoters and are involved in important biological processes ...
-
Chapter and Conference Paper
Real-Time Monitoring of Aircraft Engines Using a Feedforward Deep Neural Network
Real-time engine condition monitoring requires efficient performance parameter prediction models. Due to the highly nonlinear and dynamic characteristics of the engine, it is difficult to establish a high-prec...
-
Article
Vitamin D3/VDR inhibits inflammation through NF-κB pathway accompanied by resisting apoptosis and inducing autophagy in abalone Haliotis discus hannai
Vitamin D3 is believed to be a contributing factor to innate immunity. Vitamin D receptor (VDR) has a positive effect on inhibiting nuclear factor κB (NF-κB)-mediated inflammation. The underlying molecular mechan...
-
Article
Dermatological and Gastrointestinal Manifestations of Cronkhite-Canada Syndrome
-
Article
Defect classification on limited labeled samples with multiscale feature fusion and semi-supervised learning
Defect inspection is an essential part of ensuring the quality of industrial products. Deep learning has achieved great success in defect inspection when a large number of labeled samples are available. Howeve...
-
Article
Image classification method on class imbalance datasets using multi-scale CNN and two-stage transfer learning
Image classification tasks widely exist in many actual scenarios, including medicine, security, manufacture and finance. A major problem that hurts algorithm performance of image classification is the class im...
-
Article
Open AccessDietary carbohydrates influence muscle texture of olive flounder Paralichthys olivaceus through impacting mitochondria function and metabolism of glycogen and protein
The present study was conducted to estimate the effects of dietary carbohydrates on muscle quality and the underlying mechanisms. Six isonitrogenous and isolipidic diets were formulated to contain graded level...
-
Article
Morpho-physiological and biochemical responses of tolerant and sensitive rapeseed cultivars to drought stress during early seedling growth stage
The edible oil production in China is highly dependent on the screening and development of drought-resistant rapeseed cultivars especially in water stress areas. However, for the successful production of rapes...
-
Article
Open AccessChronic stress of high dietary carbohydrate level causes inflammation and influences glucose transport through SOCS3 in Japanese flounder Paralichthys olivaceus
Carnivorous fish is thought to be high-glucose intolerance. But the reasons were still unclear. The aim of the present study is to investigate the effects of high level of dietary carbohydrate on the survival,...