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Article
Open AccessEpigenetic modification of PKMζ rescues aging-related cognitive impairment
Cognition is impacted by aging. However, the mechanisms that underlie aging-associated cognitive impairment are unclear. Here we showed that cognitive decline in aged rats was associated with changes in DNA me...
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Article
Open AccessPredictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood
Early-life stress in adolescence has a long-lasting influence on brain function in adulthood, and it is mostly recognized as a predisposing factor for mental illnesses, such as anxiety and posttraumatic stress...
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Article
Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects
Immune dysregulation, specifically of inflammatory processes, has been linked to behavioral symptoms of depression in both human and rodent studies. Here, we evaluated the antidepressant effects of immunizatio...
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Article
Open AccessCareer choice and influential factors among medical students majoring in psychiatry in China
The undergraduate program of psychiatry has been widely established in recent years to improve the education and recruitment of psychiatrists in China. We aim to investigate the career choice of medical studen...
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Article
Open AccessWorkforce situation of the Chinese mental health care system: results from a cross-sectional study
High-quality mental health services can improve outcomes for people with mental health problems and abate the burden of mental disorders. We sought to identify the challenges the country’s mental health system...
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Article
Association between alcohol consumption and sleep traits: observational and mendelian randomization studies in the UK biobank
Previous studies have shown that excessive alcohol consumption is associated with poor sleep. However, the health risks of light-to-moderate alcohol consumption in relation to sleep traits (e.g., insomnia, sno...