27 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Ji-Eun Park
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Article
Open AccessFacile and Gram-scale Synthesis of Metal-free Catalysts: Toward Realistic Applications for Fuel Cells
Although numerous reports on nonprecious metal catalysts for replacing expensive Pt-based catalysts have been published, few of these studies have demonstrated their practical application in fuel cells. In thi...
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Article
Open AccessMicrotubule-associated protein light chain 3 is involved in melanogenesis via regulation of MITF expression in melanocytes
Although autophagy plays a role in melanogenesis by regulating melanosome degradation and biogenesis in melanocytes, a detailed understanding of the regulatory functions of autophagy factors is lacking. Here, ...
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Article
Open AccessMidterm results of coracoclavicular stabilization with double augmentation for acute acromioclavicular dislocation
Numerous techniques have been introduced for the treatment of acute acromioclavicular (AC) joint dislocation. We aim to report the midterm results of coracoclavicular (CC) stabilization with double augmentatio...
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Article
Open AccessEctopic pregnancy incidence in the Republic of Korea in 2009–2015: A population-based cross-sectional study
We estimated the incidence of ectopic pregnancy (EP) and the success rate of expectant management of EP in South Korea. We analyzed data from 2009 to 2015 using the Health Insurance Review and Assessment Servi...
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Article
Open AccessH727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth
The second-in-class proteasome inhibitor (PI) carfilzomib (Kyprolis, Cfz) has contributed to a substantial advancement in multiple myeloma treatment by improving patient survival and quality of life. A conside...
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Article
Open AccessRadiomic features and multilayer perceptron network classifier: a robust MRI classification strategy for distinguishing glioblastoma from primary central nervous system lymphoma
We aimed to establish a high-performing and robust classification strategy, using magnetic resonance imaging (MRI), along with combinations of feature extraction and selection in human and machine learning usi...
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Article
Open AccessPrognostic implications of soluble programmed death-ligand 1 and its dynamics during chemotherapy in unresectable pancreatic cancer
In pancreatic cancer, acquiring a sufficient amount of tumor tissue is an obstacle. The soluble form of PD-L1 (sPD-L1) may have immunosuppressive activity. Here, we evaluated the prognostic implications of sPD...
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Article
Open AccessPRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
The kinase Aurora B forms the chromosomal passenger complex (CPC) together with Borealin, INCENP, and Survivin to mediate chromosome condensation, the correction of erroneous spindle-kinetochore attachments, a...
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Article
Open AccessRadiomics prognostication model in glioblastoma using diffusion- and perfusion-weighted MRI
We aimed to develop and validate a multiparametric MR radiomics model using conventional, diffusion-, and perfusion-weighted MR imaging for better prognostication in patients with newly diagnosed glioblastoma....
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Article
Open AccessRobust performance of deep learning for distinguishing glioblastoma from single brain metastasis using radiomic features: model development and validation
We evaluated the diagnostic performance and generalizability of traditional machine learning and deep learning models for distinguishing glioblastoma from single brain metastasis using radiomics. The training ...
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Article
Open AccessSurvival outcome and prognostic factors in anaplastic oligodendroglioma: a single-institution study of 95 cases
The aim of this study was to evaluate prognostic factors including surgical, radiographic, and histopathologic analyses in anaplastic oligodendroglioma (AO) patients. We reviewed the electronic records of 95 p...
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Article
Open AccessDeep-learned time-signal intensity pattern analysis using an autoencoder captures magnetic resonance perfusion heterogeneity for brain tumor differentiation
Current image processing methods for dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) do not capture complex dynamic information of time-signal intensity curves. We investigated whether a...
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Article
Open AccessDifferentiation of recurrent glioblastoma from radiation necrosis using diffusion radiomics with machine learning model development and external validation
The purpose of this study was to establish a high-performing radiomics strategy with machine learning from conventional and diffusion MRI to differentiate recurrent glioblastoma (GBM) from radiation necrosis (...
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Article
Open AccessRisk of QT prolongation through drug interactions between hydroxychloroquine and concomitant drugs prescribed in real world practice
Hydroxychloroquine has recently received attention as a treatment for COVID-19. However, it may prolong the QTc interval. Furthermore, when hydroxychloroquine is administered concomitantly with other drugs, it...
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Article
Open AccessGenerative adversarial network for glioblastoma ensures morphologic variations and improves diagnostic model for isocitrate dehydrogenase mutant type
Generative adversarial network (GAN) creates synthetic images to increase data quantity, but whether GAN ensures meaningful morphologic variations is still unknown. We investigated whether GAN-based synthetic ...
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Article
Open AccessCombination of automated brain volumetry on MRI and quantitative tau deposition on THK-5351 PET to support diagnosis of Alzheimer’s disease
Imaging biomarkers support the diagnosis of Alzheimer’s disease (AD). We aimed to determine whether combining automated brain volumetry on MRI and quantitative measurement of tau deposition on [18F] THK-5351 P...
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Article
Open AccessStability of MRI radiomic features according to various imaging parameters in fast scanned T2-FLAIR for acute ischemic stroke patients
From May 2015 to June 2016, data on 296 patients undergoing 1.5-Tesla MRI for symptoms of acute ischemic stroke were retrospectively collected. Conventional, echo-planar imaging (EPI) and echo train length (ET...
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Article
Open AccessThe relationship between ultrasound findings and thyroid function in children and adolescent autoimmune diffuse thyroid diseases
To evaluate the association between thyroid echogenicity and heterogeneity seen on ultrasonography (US) and thyroid function in pediatric and adolescent populations with autoimmune diffuse thyroid diseases (AI...
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Article
Open AccessDeep learning-based thin-section MRI reconstruction improves tumour detection and delineation in pre- and post-treatment pituitary adenoma
Even a tiny functioning pituitary adenoma could cause symptoms; hence, accurate diagnosis and treatment are crucial for management. However, it is difficult to diagnose a small pituitary adenoma using conventi...
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Article
Open AccessSurface potential modulation as a tool for mitigating challenges in SERS-based microneedle sensors
Raman spectroscopic-based biosensing strategies are often complicated by low signal and the presence of multiple chemical species. While surface-enhanced Raman spectroscopy (SERS) nanostructured platforms are ...
