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  1. Article

    Open Access

    PKD2 founder mutation is the most common mutation of polycystic kidney disease in Taiwan

    Autosomal Dominant polycystic kidney disease (ADPKD) is the most common inherited adult kidney disease. Although ADPKD is primarily caused by PKD1 and PKD2, the identification of several novel causative genes in ...

    Chih-Chuan Yu, An-Fu Lee, Stefen Kohl, Ming-Yen Lin, Siao Muk Cheng… in npj Genomic Medicine (2022)

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    Article

    The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

    Currently, there are few options for treating chronic kidney disease. The immunosuppressant cyclosporine A is effective, but the mechanism has been unclear. In this new report, the authors now show that the be...

    Christian Faul, Mary Donnelly, Sandra Merscher-Gomez, Yoon Hee Chang… in Nature Medicine (2008)