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Article
Open AccessSafety and Effectiveness of SB2 (Infliximab Biosimilar) in Adult Patients with Immune-Mediated Inflammatory Diseases: A Post-Marketing Surveillance in Korea
SB2 is a biosimilar of infliximab (IFX), which is approved for rheumatoid arthritis (RA), ankylosing spondylitis (AS), adult and pediatric Crohn’s disease (CD), adult and pediatric ulcerative colitis (UC), pso...
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Article
Open AccessNutrient regulation of lipochitooligosaccharide recognition in plants via NSP1 and NSP2
Many plants associate with arbuscular mycorrhizal fungi for nutrient acquisition, while legumes also associate with nitrogen-fixing rhizobial bacteria. Both associations rely on symbiosis signaling and here we...
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Article
Open AccessDiagnostic performance of automated, streamlined, daily updated exome analysis in patients with neurodevelopmental delay
The diagnostic yield of whole-exome sequencing (WES) varies from 30%–50% among patients with mild to severe neurodevelopmental delay (NDD)/intellectual disability (ID). Routine retrospective reanalysis of undi...
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Article
Long-term outcomes of endoscopic resection followed by additional surgery after non-curative resection in undifferentiated-type early gastric cancer: a nationwide multi-center study
Undifferentiated-type early gastric cancer (UD EGC) shows lower curative resection rates after endoscopic submucosal dissection (ESD). Additional surgery is recommended after non-curative resection. We evaluat...
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Article
Prediction model for curative endoscopic submucosal dissection of undifferentiated-type early gastric cancer
Endoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer (EGC); however, its curative resection rate is low for undifferentiated-type EGC. We developed and externally validated...
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Article
Open AccessPhenotypic and molecular spectra of patients with switch/sucrose nonfermenting complex-related intellectual disability disorders in Korea
The switch/sucrose nonfermenting (SWI/SNF) complex is an adenosine triphosphate-dependent chromatin-remodeling complex associated with the regulation of DNA accessibility. Germline mutations in the components ...
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Article
Comparison between endoscopic submucosal resection and surgery for the curative resection of undifferentiated-type early gastric cancer within expanded indications: a nationwide multi-center study
Endoscopic submucosal dissection (ESD) for undifferentiated early gastric cancer (UD EGC) has debate due to the risk of lymph node metastasis. We investigated the outcomes of ESD compared to those of surgery f...
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Article
Improvement of Medication Adherence and Controlled Drug Release by Optimized Acetaminophen Formulation
Acetaminophen (paracetamol, APAP) is a major component of Tylenol, Penzal Q, and Panpyrin, and is the most commonly used antipyretic analgesic in children. The conventional oral drug delivery systems of APAP a...
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Article
Release Behavior of Telmisartan/Amlodipine Combination Drug According to Polymer Type
Patients at risk for hypertension with comorbidities such as diabetes and metabolic syndrome often require two or more antihypertensive drugs to lower their blood pressure. Telmisartan and amlodipine are widel...
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Article
Clinical outcomes of endoscopic resection for undifferentiated intramucosal early gastric cancer larger than 2 cm
This study investigated the long-term clinical outcomes of endoscopic resection (ER) for undifferentiated-type (UD) early gastric cancer (EGC), with tumor size > 2 cm as the only non-curative factor.
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Article
Risk factors of lymph node metastasis after non-curative endoscopic resection of undifferentiated-type early gastric cancer
This study aimed to investigate risk factors for lymph node (LN) or distant metastasis after non-curative endoscopic resection (ER) of undifferentiated-type early gastric cancer (EGC).
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Article
Open AccessThe negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice
Most plants associate with beneficial arbuscular mycorrhizal (AM) fungi that facilitate soil nutrient acquisition. Prior to contact, partner recognition triggers reciprocal genetic remodelling to enable coloni...
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Article
Open AccessAIMS65 scoring system is comparable to Glasgow-Blatchford score or Rockall score for prediction of clinical outcomes for non-variceal upper gastrointestinal bleeding
Risk stratification for patients with nonvariceal upper gastrointestinal (NVUGI) bleeding is crucial for successful prognosis and treatment. Recently, the AIMS65 score has been used to predict mortality risk a...
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Molecular Mechanism of Plant Recognition of Extracellular ATP
Adenosine 5′-triphosphate (ATP), a ubiquitously dispersed biomolecule, is not only a major source of biochemical energy for living cells, but also acts as a critical signaling molecule through inter-cellular c...
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Article
Clinical outcomes of no residual disease in the specimen after endoscopic resection for gastric neoplasms
No residual disease (NRD) can be found in the specimen after endoscopic resection (ER) of biopsy-proven gastric neoplasm. This study aimed to evaluate the endoscopic and pathologic characteristics of patients ...
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Article
Endoscopic predictors for undifferentiated histology in differentiated gastric neoplasms prior to endoscopic resection
There is often a discrepancy between results from endoscopic forceps biopsy and resected specimen. We aimed to identify endoscopic predictors for undifferentiated histology in differentiated gastric neoplasms ...
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Article
Risk factors of delayed ulcer healing after gastric endoscopic submucosal dissection
Although post-endoscopic submucosal dissection (ESD) iatrogenic ulcer is known to heal faster than peptic ulcer, some iatrogenic ulcers show delayed healing. The aim of this study was to clarify risk factors o...
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Article
Risk factors for synchronous or metachronous tumor development after endoscopic resection of gastric neoplasms
Despite many advantages, the development of synchronous or metachronous neoplasm is one of the main concerns with endoscopic resection. We aimed to clarify the independent risk factors for synchronous or metac...
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Article
Long-term clinical outcomes of endoscopic resection for early gastric cancer
We aimed to evaluate long-term clinical outcomes of endoscopic resection for early gastric cancer (EGC).
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Article
Predictors of lymph node metastasis in patients with non-curative endoscopic resection of early gastric cancer
Although surgery is recommend for non-curative endoscopic resection of early gastric cancer (EGC), only a part of patients are found to have lymph node (LN) metastasis. This study aimed to identify the predict...
