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Article
Next-generation biocontainment systems for engineered organisms
The increasing use of engineered organisms for industrial, clinical, and environmental applications poses a growing risk of spreading hazardous biological entities into the environment. To address this biosafe...
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Article
'Deadman' and 'Passcode' microbial kill switches for bacterial containment
Synthetic biology has expanded the availability of engineered bacterial systems for diverse applications and is now develo** safeguards for their effective and secure use. The report of two synthetic gene ci...
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Article
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
Growing concerns over limited fossil resources and associated environmental problems are motivating the development of sustainable processes for the production of chemicals, fuels and materials from renewable ...