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    Article

    Next-generation biocontainment systems for engineered organisms

    The increasing use of engineered organisms for industrial, clinical, and environmental applications poses a growing risk of spreading hazardous biological entities into the environment. To address this biosafe...

    Jeong Wook Lee, Clement T. Y. Chan, Shimyn Slomovic in Nature Chemical Biology (2018)

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    'Deadman' and 'Passcode' microbial kill switches for bacterial containment

    Synthetic biology has expanded the availability of engineered bacterial systems for diverse applications and is now develo** safeguards for their effective and secure use. The report of two synthetic gene ci...

    Clement T Y Chan, Jeong Wook Lee, D Ewen Cameron, Caleb J Bashor in Nature Chemical Biology (2016)

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    Article

    Systems metabolic engineering of microorganisms for natural and non-natural chemicals

    Growing concerns over limited fossil resources and associated environmental problems are motivating the development of sustainable processes for the production of chemicals, fuels and materials from renewable ...

    Jeong Wook Lee, Dokyun Na, Jong Myoung Park, Joungmin Lee in Nature Chemical Biology (2012)