6 Result(s)
within
Jens Keilwagen
Microarrays
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Article
Open AccessChromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical...
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Article
Open AccessCombining RNA-seq data and homology-based gene prediction for plants, animals and fungi
Genome annotation is of key importance in many research questions. The identification of protein-coding genes is often based on transcriptome sequencing data, ab-initio or homology-based prediction. Recently, it ...
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Article
Open AccessAssociation genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes
Understanding the genetic basis of frost tolerance (FT) in wheat (Triticum aestivum L.) is essential for preventing yield losses caused by frost due to cellular damage, dehydration and reduced metabolism. FT is a...
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Article
Open AccessDiffLogo: a comparative visualization of sequence motifs
For three decades, sequence logos are the de facto standard for the visualization of sequence motifs in biology and bioinformatics. Reasons for this success story are their simplicity and clarity. The number of i...
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Article
Open AccessApples and oranges: avoiding different priors in Bayesian DNA sequence analysis
One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or silencers, translation initiation sites, t...
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Article
Open AccessUnifying generative and discriminative learning principles
The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of different and well-adapted models has been develo...
